Reach Us +44-1625-708989
Endothelial Micro-particles In Patients With Chronic Kidney Disease And Cardiovascular Disease | 49096
ISSN: 2155-9880

Journal of Clinical & Experimental Cardiology
Open Access

Like us on:

Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Endothelial micro-particles in patients with chronic kidney disease and cardiovascular disease

International Conference on Cardiovascular Medicine

Carolina Nunes Franca

University of Santo Amaro, Brazil Federal University of Sao Paulo, Brazil

Posters & Accepted Abstracts: J Clin Exp Cardiolog

DOI: 10.4172/2155-9880.C1.039

Introduction: Chronic kidney disease is characterized by loss, normally gradual and progressive, of the excretory capacity by kidneys and constitutes a serious public health problem and higher rate of cardiovascular events as acute myocardial infarct, stroke and mortality when compared to the general population. Endothelial micro-particles are shed by the membrane of different cell types after activation or apoptosis and are related to classic risk factors and cardiovascular disease. Objective: Evaluate if the progression of kidney disease is related to the increase in circulating endothelial micro-particles, in patients with established cardiovascular disease. Methods: Some variables related to kidney disease (urine and serum creatinine, albumine/creatinine relation, glomerular filtration rate) were correlated with endotelial micro-particle levels, in patients with cardiovascular disease (n=84), comparing the values obtained to micro-particles according to the stage of kidney failure. Results: There were no significant correlations between the parameters evaluated (correlation between endothelial micro-particles and serum creatinine [Spearman, rho = -0,208; p = 0,064]; correlation between endothelial micro-particles and glomerular filtration rate [Spearman, rho = 0.194, p = 0.085]), other correlations also not significant. Conclusion: There was no evidence concerning the increase of endothelial micro-particles related to the progression of kidney disease in patients with cardiovascular disease.

Carolina Nunes França has completed her PhD from Federal University of Sao Paulo, Brazil and Post-doctoral studies from University of Bonn, Germany. She is Professor of University of Santo Amaro – UNISA (Health Science Post Graduation), Brazil. She has published more than 36 papers in reputed journals.

Email: [email protected]