alexa Enhancement Of Neural Regeneration After Spinal Cord Injury Using Muscle Graft | 63424
ISSN: 2157-7013

Journal of Cell Science & Therapy
Open Access

Like us on:

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

8th World Congress and Expo on Cell & Stem Cell Research

Bassem Essam Mostafa Mahmoud, Hala Gabr, Mohamed M. Refaat, Haithem A.M. Farghali, Maha Zickri, Amal Elham fares, Shaimaa El-Jaafary, Mostafa Abdallah Madbouly, Mohamed Abdelfadel Awad Abdelfadel and Ali Mohamed Hammad
Cairo university
Benisuwif University
ScientificTracks Abstracts: J Cell Sci Ther
DOI: 10.4172/2157-7013.C1.038
Abstract
Background: Spinal cord injury is one of the most important problems facing the world, not only poor countries but also highincome countries. The responsibility of rehabilitation of disabled patients causes a huge financial burden on governments that provide facilities, as well as on patients themselves and societies who pay for their social care (1) .Every year, about 250,000 to 500,000(2) new disabled persons are added to the worldwide burden of patients with TSCI. In USA alone, about 12,000 are added every year (3) In addition to 906 for every million presented in 2014 (4). In Canada, about 1,785 annually (5) .In another area as Australia there is about 14.5 for every million every year (6) .And locally in Egypt there are about 18 TSCI cases for every 100,000 of population (7) Aim of work: Evaluate the clinical efficacy of muscle grafting in enhancing neural recovery in canine model of traumatic spinal cord injury. Subjects & Methods: 1. The study subjects were divided into active (muscle graft) and control groups. Six adult dogs included in each group. 2. Induction of SCI model: Dorsal laminectomy (8) was performed with longitudinal incision of the dura then excision of one cm segment of the spinal cord was performed at the mid thoracic region. 3. Graft preparation: muscle graft was taken from the latissimus dorsi muscle during surgery then the dura was repaired to prevent CSF leakage. 4. Grafting procedures: the muscle graft was prepared to fit inside the gap between the proximal end and the distal end of the spinal cord. 5. Follow up: evaluation of recovery was done by: - Clinical scoring: By using Olby score(9) - Histological examination: H&E sections were examined and showed overgrowth of axons on the muscle graft and the section started to organize as central gray matter and peripheral white matter. CD44 stain was positive for endogenous stem cells. Results and Conclusions: This study proves the clinical efficacy of muscle grafting as a tool for induction of neuro regeneration after spinal cord injury.
image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
Leave Your Message 24x7