alexa Equipoise: The Guiding Ethical Principle Pertaining To Randomized Clinical Trials | 72901
ISSN: 2167-0870

Journal of Clinical Trials
Open Access

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4th International Conference on Clinical Trials

Scott Gelfand
Oklahoma State University, USA
ScientificTracks Abstracts: J Clin Trials
DOI: 10.4172/2167-0870-C1-019
Abstract
In 1972, Charles Fried, in Medical Experimentation: Personal Integrity and Social Policy asserted that physician-researchers have an ethical obligation to be in a state of equipoise during all stages of randomized clinical trials. Fried’s equipoise requirement dictates that a physician engaged in research must not believe that one experimental arm of a randomized clinical trial is better or more efficacious than the other arms (must be in a state of equipoise). Although the equipoise requirement has been modified over the course of the last 45 years, the equipoise requirement is currently the fundamental or guiding principle concerning the ethics of enrolling patients in randomized clinical trials. In this talk I will discuss the ethical foundation for the equipoise requirement, what is the current equipoise requirement and ethical/practical problems associated with the equipoise requirement.
Biography

Scott Gelfand received his Ph.D. in Philosophy from the University of Maryland and his J.D. from Georgetown University Law Center. He is a tenured professor and Head of the Department of Philosophy at Oklahoma State University. His research is focused primarily on issues in biomedical ethics and research ethics. In 2010 he received an NSF grant to develop a novel research ethics course for scientists and engineers.

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