alexa
Reach Us +441414719275
Evaluation Of Matrix Metalloproteinases, Their Inhibitors And Their Participation In Cervical Carcinogenesis | 9617
ISSN: 2157-7552

Journal of Tissue Science & Engineering
Open Access

Like us on:

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

2nd International Conference on Tissue Science & Regenerative Medicine

Jacintoda Costa Silva Neto
ScientificTracks Abstracts: J Tissue Sci Eng
DOI: 10.4172/2157-7552.S1.010
Abstract
T he cervical cancer is the third among cancers in women worldwide. Studies have confirmed that infection followed by persistent human papillomavirus (HPV) plays a major role in the onset and progression of cervical lesions. Among the viral mechanisms of induction of cancer are the oncoproteins E6 and E7, with the ability to modify the host cell cycle and contribute to the process of uncontrolled cell progression. However, only HPV infection is not able to induce invasive lesions are required cofactors, including matrix metalloproteinases (MMP) family of endopeptidases capable of digesting the extracellular matrix and basal membrane factors induce development consequently participates the processes of neoplastic invasion, metastasis, angiogenesis, and tumor recurrence. In neoplastic lesions MMPs are produced by tumor cells and stromal cells involved in the vicinity of neoplastic lesions. Although much studied, little is known about the mechanisms of MMPs in cervical lesions and HPV. Most studies were performed using cultured cells infected with HPV-16 or 18 are missing in the presence of research and coinfection synthesis and activation of MMPs, including subtypes. So what is the role of matrix metalloproteinases and inhibitors (TIMP and RECK) in the progression of cervical lesions (squamous intraepithelial lesions until the invasion), matching them to the type of HPV and expression of oncoproteins E6, E7? These proteins would be predictive and diagnostic markers in tumor progression and invasion?
Biography
Jacintoda Costa Silva Neto was 23 years old when he completed his degree. He has an B.Sc.. in biophysics, a specialist in cytopathology at the Federal University of Pernambuco and a Ph.D. in pathology from the University of S?o Paulo. He is currently an Assistant Professor, and coordinator of the cytopathology sector and of postgraduate cytopathology. He is also Head of the Laboratory of Molecular and Cytological Research at the Federal University of Pernambuco and leader of the Research Group on Chronic-Degenerative Diseases-CNPq/UFPE. He also develops cancer research (biomarkers, adhesion molecules and mechanisms metastatic) and has published several articles in scientific journals, including mechanisms of carcinogenic human Papillomavirus, and tissue morphofunctional disorders in the use of natural extracts
image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri and Aquaculture Journals

Dr. Krish

[email protected]

+1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version