ow pathogenic avian influenza viruses (H9N2) is circulating in poultry industry of many Euroasian countries causing
serious economical problems. In this study we investigated clinical signs, antibody response, viral shedding and efficacy of
oil emulsion vaccines in chukar partridges. Seventy five chukar partridges (Alectoris chukar) were divided randomly in three
groups of 1-Challenged, 2- Vaccinated and challenged 3-Control (non-vaccinated and non-challenged) groups 25 birds/group.
In challenged and vaccinated groups birds were inoculated with 0.4 ml allantoic fluid containing 107 EID50/bird of tA/Chicken/
Iran/772/1998(H9N2) avian influenza virus. Clinical signs, antibody response, viral shedding and vaccine efficacy were evaluated
and compared among these groups. Clinical signs such as; coughing and sneezing with depression and decreased in feed and
water consumption were observed in group one. Also in vaccinated and challenged group slight decrease of food and water
consumption were observed. Both vaccinated and challenged groups showed maximum antibody titer at 9 DPI. At 1 DPI the
virus was detected from all tissues in challenged group, however the virus wasn?t detected from the spleen and cecal tonsil of
group vaccinated and challenged group. Unvaccinated challenged groups showed longest period of viral shedding in the trachea
Professor Hassan Nili has completed his Ph.D at Queensland University in Australia and he his study leave research at VLA in UK on highly
pathogenic avian influenza viruses. He is currently the head of avian diseases research center of Shiraz University. He has been involved in
Influenza research for more than 10 years.
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