alexa Evaluation Of Toxicity And Genotoxic Effects Of Catheranthus Roseus (linn) Extract On Drosophila Melanogaster: Stress Protein And Wing Contour Bioassay
ISSN: 2168-9881

Agrotechnology
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Share This Page

Additional Info

Loading
Loading Please wait..
 

3rd International Conference on Agriculture & Horticulture
October 27-29, 2014 Hyderabad International Convention Centre, India

Soumya K, and Y Shibu Vardhan
Posters: Agrotechnol
DOI: 10.4172/2168-9881.S1.012
Abstract
Catheranthus roseus has historically been used to treat a wide variety of diseases. The present study aimed to demonstrate a dose dependant effect of C. roseus ethanol extract to Drosophila melanogaster and develop an ideal tool for evaluating genotoxicity assessment of several medicinal plant compounds of therapeutic use. The evaluation was made using stress protein profile analysis and wing contour bioassay. The treatments for the battery toxicity assays were 3mg/ml, 1.5 mg/ml and 0.1875 mg/ml ethanol extractable fraction from Catheranthus roseus dry powder. A control and ethanol control was also included in treatments. Three sets of experiments were run simultaneously, first and second for wing contour study and the third set for protein profile analysis. The battery toxicity bio assays helped to demonstrate the chemotaxic behavioral response of intoxicated larvae. The papal color was, brown with dark spots, dark brown, and dark brown respectively in 3, 1.5 and 0.1875 mg/ml doses. Whereas it was light brown and brown in control and ethanol control. Stress protein studies helped to exemplify the sub cellular action of chemicals in test organism. The elicitation of different proteins with apparent molecular weights 109,45,36,28 and 11 KDa expressed during exposure and organism showed a dose depended effect. Wing contour bioassay results showed both dose and exposure time, governs the toxicity and genotoxicity effects in Drosophila larvae. Most of the vein intersection points showed slight tendency of dextral rotation. The present study results indicates higher dose of ethnopharmasueticals cause very strong impact on organisms and it is similar to that of any xenobiotics.
Biography
Soumya K is currently working as a research fellow in Indian Institute of Horticultural Research; Bangalore. She is presently engaged in research on biological control of horticultural crop pests.
image PDF   |   image HTML
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]ine.com

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords