alexa Expandable Polyurethane Stent Valve, As An Option For Pediatric Patients With Valve Diseases: Result Of Physical, Hydrodynamic And Experimental Studies
ISSN: 2155-9880

Journal of Clinical & Experimental Cardiology
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

World Heart Congress
May 22- 24, 2017 Osaka, Japan

Miguel A Maluf, Mariana G Massei, Rogerio Orbetelli, Miko Obradovic, Christian Bader, Christoph Klaus, Evandro Drigo, Mauricio R Vaz, Andre Gimenes, Fernando Zanini, Jayme Ortiz and Ovandir Bazan
Universidade Federal de São Paulo, Brazil
Bentley InnoMed GmbH, Germany
Centro de Engenharia em Assistência Circulatória – IDPC, Brazil
Instituto do Coração da Universidade de São Paulo, Brazil
Polytechnic School of the University of São Paulo, Brazil
Posters & Accepted Abstracts: J Clin Exp Cardiolog
DOI: 10.4172/2155-9880-C1-069
Abstract
Background: An expandable polyurethane (PU) stent valve, with a special design for pediatric patients, may be an option for biological prostheses whose calcification or mismatch, in child's development, shorten their durability. (Average of 5 years) Methods: 1- In vitro tests: I- Physical test: The prostheses were submitted to universal tests, of samples of PU, pre and post crimping: A- Strength versus deformation (stretching). B- Scanner for surface and electrical and mechanical properties using Atomic Force Microscopy. II- Hydrodynamic test: Using a pulsatile flow, for study of valvular area, gradient and regurgitation, under physiological and stress conditions, using 12, 15, 18 and 22 mm valve stent diameters. 2- In vivo test: III- Experimental: 10 sheep were submitted to implantation of prosthesis by catheter, in pulmonary position. Expansion diameter: Group A: 22mm (7 cases) and Group B: 18mm (3 cases) Results: I - In vitro tests: PU showed to be a thermoplastic structure with high deformation, resistant to crimping and elongation. The hydrodynamic test showed low gradients, regardless of the diameter of the prosthesis. In vivo tests: After 5 months of implantation of the prosthesis in sheep, the 3D echocardiographic study showed: satisfactory hemodynamic performance, with no significant transvalvular gradient (5.80 to 10 mmHg, M = 6.92 mmHg), no regurgitation and calcification-free of the PU leaflet. Discussion: Published papers on the durability of bio-prosthetic devices in pediatric patients show that 20 to 30% of patients are free of reoperation after 9 years of follow-up. The development of the pediatric patient with cardiac prosthesis causes mismatch that requires the replacement of the prosthesis until adulthood. Conclusions: Monitoring of favorable results confirms that the PU valve stent can be implanted in children, below 5 years, during conventional surgery and above 7 years, by catheter implantation.
Biography

Email: [email protected]

image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version