UHN Toronto Western Hospital, Department of Ophthalomology, Ontario Delayed diagnosis
of choroidal-neovascularization (CNV) in age- related macular degeneration (AMD)
adversely affects visual outcome.
We aim to identify factors associated with early detection of CNV in the clinic setting.
Demographics, clinical data and lesion characteristics were retrospectively collected from
76 consecutive AMD patients who had history of CNV in one eye and presented with CNV in the
second eye and evaluated for association with visual acuity (VA) at time of presentation.
Better VA was associated with history of CNV in the fellow eye (p<0.0001), adherence to
follow-up every four-months (p=0.015), younger age (p=0.03), smaller lesion (p<0.0001), and non-
subfoveal location (p=0.048). VA of the fellow eye did not correlate with VA at presentation with
These data suggest that experience of CNV, regardless of VA, facilitates early diagnosis in the fellow eye. Adherence to
follow-up in the routine clinic setting also facilitates early detection of CNV.
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