alexa From Complete Catalogs To | 9356
ISSN: 0974-7230

Journal of Computer Science & Systems Biology
Open Access

Like us on:

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

International Conference on Integrative Biology Summit

Han Liang
Accepted Abstracts: J Comput Sci Syst Biol
DOI: 10.4172/0974-7230.S1.004
Abstract
Next-generation sequencing has become a revolutionary tool for cancer research. However, there is still a big gap between complete catalogues of genomic alternations identified from NGS studies and ?actionable? shortlists for further functional investigation. Using my two recent studies (RNA-seq in gastric cancer and exome-seq in endometrial cancer), I will discuss how to identify ?driver? genes underlying the tumorigenesis. In the first study, we performed a comprehensive analysis on the whole-transcriptome of gastric cancer, and developed a multilayer and integrative analytic framework for identifying potential therapeutic targets from RNA-seq data (Kim et al., Cancer Research 2012). In the second study, we developed an integrated systems-biology approach to identifying driver somatic mutations from whole-exome sequencing data, which combines bioinformatics prioritization, a high-throughput approach to generating mutants and high-through cell viability assays (Liang et al., Genome Research 2012).
Biography
Liang received Ph.D. training from the Quantitative and Computational Biology program at Princeton University in 2006. As a postdoctoral researcher, Dr. Liang completed three years of research on computational and evolutionary genomics at the University of Chicago. Currently, Dr. Liang is an Assistant Professor in the Department of Bioinformatics and Computational Biology at the University of Texas MD Anderson Cancer Center and he is also a faculty member in Graduate Program in Structural & Computational Biology & Molecular Biophysics in Baylor College of Medicine. His research interests include the analysis of next-generation sequencing data, the integration of cancer genomics data, microRNA regulation, and the evolutionary process of tumor cells.
image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

kactakapaniyor.com

[email protected]

+1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

Taktube

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

porn sex

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

Gaziantep Escort

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

sikiş

[email protected]

1-702-714-7001Extn: 9037

instafollowers

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

mp3 indir

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

putlockers

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

seks

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version