alexa Hereditary Or Maternal Hypertension Damage Offspring Kidneys In Rats | 16629
ISSN: 2155-9880

Journal of Clinical & Experimental Cardiology
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

4th International Conference on Clinical & Experimental Cardiology
April 14-16, 2014 Hilton San Antonio Airport, TX, USA

Sonia Regina Jurado
Posters: J Clin Exp Cardiolog
DOI: 10.4172/2155-9880.S1.020
Abstract
The objective of the study was to analyze the effect of hereditary hypertension or induced by chronic nitric oxide inhibition during pregnancy on glomeruli and microvasculature of the kidneys in fetal and neonates. Total nine sub-groups allocated from 3 main groups of fetuses (20 th d) and newborns (2 nd and 15 th d) offspring?s from normotensive mothers (C), SHR and L-NAME was performed. The right kidney from fetuses and newborns were removed, seccioneted and stained by hematoxylin and eosin. Pro-Plus image analysis system was used to performing the quantitative analyses. The glomerular area and the number of glomeruli per area were determined per animal in 25 fields. Also, it was assessed the thickness of tunica media of renal micro vessels. The significant difference (*) was considered if P<0.05. The nephrons number was lower in L-NAME (2.18?0.82*; 2.18?0.73*) group compared to C (2.51?0.83; 2.71?0.79) at 2nd and 15th d, respectively. The glomerular area in hypertensives (L-NAME: 1.80?0.46; 1.91?0.44* and SHR: 1.70?0.47*, 1.53?0.42* at 2 nd and 15 th d, respectively) was smaller than C (1.83?0.62 and 2.17?0.61, at 2 nd and 15 th d, respectively). The kidneys of hypertensives fetuses presented more connective tissues in between of renal cortex and medulla, meaning retard of development. Great accumulation of collagen was found in tubular interstitium, periadventitia, renal cortical vessels and glomeruli at 15 th d. Thickening of the media of arterioles was found in hypertensives animals at 2 nd and 15 th d compared to C. Also, wall-to-lumen ratio of arterioles was greater in hypertensive compared to C at 2 nd d. Maternal hypertension, hereditary or artificially induced, causes structural changes in the offspring rats kidneys and impairs renal development which potentially may lead to hypertension in later life.
Biography
Sonia Regina Jurado is graduated in Biological Sciences from the State University of Rio de Janeiro (1995), master in Morphology from the State University of Rio de Janeiro (1998) and Ph.D. in Pathophysiology in Clinical Medicine from the Universidade Estadual Paulista J?lio de Mesquita Filho (2005), Brazil. She is an Associate Professor in the Nursing Course at the Federal University of Mato Grosso do Sul (UFMS) and tutor group Tutorial Education in Nursing/UFMS. Professor Jurado has experience in the area of Medicine, Nursing and Biology . She has among papers in scientific journals and conference proceedings
image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version