alexa Immune And Nervous System Altogether Against A Big Antigen Called Distress | 19657
ISSN: 2155-9899

Journal of Clinical & Cellular Immunology
Open Access

Like us on:

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

3rd International Conference and Exhibition on Clinical & Cellular Immunology

Alejandro Mart?nez-Mart?nez and Alejandra Vargas-Caraveo
Posters: J Clin Cell Immunol
DOI: 10.4172/2155-9899.S1.018
Abstract
Chronic emotional distress creates an evident cross-talk among immune and nervous systems guiding mind, brain and body to communicate and overcome this adverse stimulus, that if not controlled becomes one of the major factors in developing degenerative diseases. A chronic exposure to a stressor entails inflammatory responses in the brain and the rest of the body. Extensively, cytokines, hormones and neuropeptides have been described as intermediaries between brain and immune system during a emotional distress condition. We have demonstrated that the neuroinflammation caused by distress induces, in a lack of blood-brain-barrier structure such as Area postrema (AP), the circulating leukocytes recruitment as well as changes in microglial morphology. We used a chronic emotional distress model on rats to study CD45 and CD11b expression by immunohistofluorescence in AP as well as TrkA neuronal marker. We found that distress induces number of immunomorphological phenotypes poorly presented in control group; interestingly CD45+ cells were able to co-express TrkA in a highly significant amount. On the other hand, by synchrotron FTIR microspectroscopy we were able to obtain the organic profile of circulating leukocytes from rats under chronic emotional distress providing unique information about the detrimental state of immune system, such as lipid peroxidation and transcriptional changes at single cell resolution. This study provides to psychoneuroimmunology new data about the inflammatory process of the CNS ought to distress sensed as an antigen by the circulatory system as the results demonstrate.
image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
Leave Your Message 24x7