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|Muhammad Khurram Waqas|
|University of Veterinary and Animal Sciences, Pakistan|
|ScientificTracks Abstracts: J Cosmo Trichol|
|The overproduction of melanin pigment causes the skin hyperpigmentation. Soybean extract inhibits the activation of the protease-activated receptor-2 (PAR-2), which is involved in the regulation of pigmentation. The current study was undertaken to investigate the skin lightening and antierythmic effects of a cosmetic emulsion containing 4% concentrated extract of soybean (Glycine max), using the base without soy bean extract as control. In the inner aqueous phase of cosmetic w/o emulsion entrapment of soybean extract was carried out. Both the base (containing no extract) and formulation (containing 3% concentrated extract of soybean) were applied to 11 healthy male volunteers for duration of 12 weeks. By using a Mexameter MPA5 (a non-invasive skin bioengineering technique) skin parameters such as skin melanin and skin erythema were evaluated for every two weeks to assess any effect produced by these cosmetic emulsions. Statistically significant (p≤0.05) decrease in skin erythema was shown by formulation while the base showed insignificant (p>0.05) decrease. Significant (p≤0.05) decrease in skin melanin contents were displayed by the formulation while the base presented a statistically insignificant (p>0.05) increase in skin melanin. The newly formulated cosmetic emulsion containing soybean extract can therefore be used safely without causing any irritation as skin lightening agent in males.|
Muhammad Khurram Waqas has completed his PhD from The Islamia University of Bahawalpur, Pakistan. He is an Assistant Professor at Institute of Pharmaceutical Sciences, University of Veterinary and Animal Sciences, Lahore, Pakistan He has published more than 20 papers in reputed journals. His main research focus on impacts of botanical extracts in cosmetics. His research objectives are to develop safe, efficacious and economical dematological products from plant extracts for the improvement of skin complexion and treatment of various dermatological disorders.
Email: [email protected]
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