alexa Influence Of Antibiotic Resistance On Plasma Susceptibility Of Multi-drug Resistant Clinical Isolates Of Enterococci
ISSN: 2157-7609

Journal of Drug Metabolism & Toxicology
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Share This Page

Additional Info

Loading
Loading Please wait..
 

3rd World Congress and Exhibition on Antibiotics and Antibiotic Resistance
July 31-August 01, 2017 | Milan, Italy

Georg Daeschlein, Sebastian von Podewils and Claudia Sicher
University Medicine Greifswald, Germany
ScientificTracks Abstracts: J Drug Metab Toxicol
DOI: 10.4172/2157-7609-C1-008
Abstract
Background: Cold atmospheric plasma (CAP) could be considered as an alternative against multi-drug resistant (MDR) pathogens. Susceptibility to CAP of clinical isolates of Enterococci depending on antibiotic resistance was investigated in pure culture regarding the most important resistance patterns. Patients & Methods: 6 groups of Enterococci (39 isolates) were treated on agar using dielectric barrier discharge plasma (DBD). These included Enterococci with combined vancomycin- and high-level gentamicin resistance, with high-level resistance to gentamicin (HLGR) only, with vancomycin resistance alone (VRE), and Enterococci susceptible to both. Isolates showing high-level resistance to gentamicin were placed together in a separate group, as well as isolates with vancomycin resistance. Susceptibility was evaluated based on the zones of inhibition (ZOI) and examined in terms of the enterococcal group and the degree of drug resistance. Results: CAP-treatment killed all groups. Significantly smaller ZOI were obtained with MDR-groups: VRE-isolates showed significantly smaller ZOI than non-VRE-isolates and HLGR-isolates showed smaller ZOI than non-HLGR-isolates. The mean of all isolates, irrespective of belonging to groups, showed smaller ZOI with increasing drug resistance. Conclusions: CAP-treatment killed all isolates of Enterococci, but its efficacy depended on the degree of drug resistance and on membership in special resistance groups with particular clinical-outbreak importance.
Biography

Georg Daeschlein received the MD degree from Christian-Albrechts-Universität Kiel, Kiel, Germany, in 1985 and specializations in Laboratory Medicine, in Microbiology and Epidemiology, in Hygiene and Environmental Medicine and in Dermatology from University Medicine Greifswald, Germany, in 1993, 1995, 2005 and 2014, respectively. In 2011, he acquired his Habilitation in Hygiene and Environmental Medicine. Since 2006, he has been the Registrar and Head of the Dermatologic Laboratory in the Department of Dermatology of the University Medicine Greifswald and conducts the research group plasma-medicine and antimicrobial procedures.

Email: [email protected]

image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords