Reach Us +1-504-608-2390
In-silico SMILES-based Toxicity Prediction Of Fluorescent Dye (Rh-B) | 67780
ISSN: 2161-0495

Journal of Clinical Toxicology
Open Access

Like us on:

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

In-silico SMILES-based toxicity prediction of fluorescent dye (Rh-B)

9th Euro-Global Summit on Toxicology and Applied Pharmacology

Charli Deepak Arulanandam and Hans-Uwe Dahms

Kaohsiung Medical University, Taiwan

Posters & Accepted Abstracts: J Clin Toxicol

DOI: 10.4172/2161-0495-C1-025

The aim of this study was to investigate the toxicity of Rhodamine B (Rh-B) via computational tools. Rh-B is a fluorescent organic dye and it has much importance because of its photo-physical properties. The ‘International Agency for Research on Cancer’ classified Rh-B in the risk category for human cancer (CAS No. 81-88-9)This illegally used food colorant was here assessed for its toxicity via computational tools. For this assessment we used LAZAR Toxicity Predictions, PROTOX and pkCSM to explore about the pharmacokinetic and toxicological properties of Rh-B. We simulated Rh-B structure based on SMILES build by ACD/ChemSketch. This assessment shows that Rh-B provides carcinogenic, hepatotoxic risk for humans with a maximum recommended tolerated dose of 0.423 log(mg/kg/day).

Charli Deepak Arulanandam is a PhD student at the Kaohsiung Medical University (KMU), Taiwan. His current research interests are screening of multi drug resistant bacteria from the marine environment and the impact of emerging antibiotic resistant genes on public health. He has assessed Rhodamine–B (fluorescent dye) toxicological properties using in silico tools.

Email: [email protected]