alexa Interaction Between The Transcriptional Machineries In Pseudorabies Virus
ISSN: 1948-5964

Journal of Antivirals & Antiretrovirals
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4th World Congress on Virology
October 06-08, 2014 Hilton San Antonio Airport, TX, USA

Zsolt Boldogkői, D?ra Tomb?cz, Zsolt Csabai, P?ter Ol?h and Michael Snyder
Posters: J Antivir Antiretrovir
DOI: 10.4172/1948-5964.S1.021
Earlier we proposed that the transcriptional interactions form a network play important roles in the regulation of global gene expression in all taxa of living beings. We used a herpesvirus model for the investigation of this issue. The genome of pseudorabies virus (PRV) is very compact. We have shown that most of the PRV transcripts overlap with each other in various manners including convergent, divergent and parallel orientations. We have shown that this interactions result in a inverse pattern of gene expressions. We used the following techniques for these investigations: Real-time RT-PCR, Illumina HiScanSQ and PacBio RS II platforms. This work was supported by Swiss-Hungarian Cooperation Programme (SH/7/2/8) to ZB, co-financed by the European Social Fund in the framework of T?MOP-4.1.1.C-13/1/KONV-2014-0001 to ZB and T?MOP 4.2.4. A/2-11-1-2012-0001 ?National Excellence Program? to DT.
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