alexa
Reach Us +44-1477412632
Interactive Study Of Emblica Officinalis With Pioglitazone In High Fat Fed/low Dose STZ Induced Diabetic Nephropathic RatsM | 6148
ISSN: 2155-6156

Journal of Diabetes & Metabolism
Open Access

Like us on:

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Interactive study of Emblica Officinalis with Pioglitazone in high fat fed/low dose STZ induced diabetic nephropathic ratsM

3rd World Congress on Diabetes & Metabolism

Karthik CH and Prem Kumar N

Posters: J Diabetes Metab

DOI: 10.4172/2155-6156.S1.019

Abstract
Diabetic nephropathy is the most important microvascular complication among type 2 diabetic patients. Oxidative stress plays a major role in the pathogenesis of diabetic nephropathy. The present study investigated the combined effect of Emblica officialise (EO) with Pioglitazone in type II diabetes induced nephropathy. Diabetes was induced in male Sprague-Dawley rats with high fat diet fed/low dose STZ injection which induced changes in the renal histopathology with concurrent decrease in antioxidative enzymes. Altered lipid profile, elevated blood glucose level, serumcreatinine, blood urea nitrogen, proteinuria was observed in diabetic control. Group I received normal pellet diet (control), group II served as diabetic control and groups III to V were treated with EO alone, Pioglitazone alone, EO plus Pioglitazone respectively. Treatment schedule was started one day before STZ injection. Treatment with combination of EO and Pioglitazone significantly attenuated the renal dysfunction when compared with groups treated alone. The beneficial effect of this combination can be attributed to the amelioration of oxidative stress induced changes in diabetic renal structure.
Biography
Karthik CH has completed his B.Pharm from Bharathi College of Pharmacy, Bharathi Nagara, Karnataka and pursuing his M.pharm from Krupanidhi College of Pharmacy, Karnataka. He attended many workshops like workshop on patents organised by IIPTA in the 2012. He participated in many seminars like Seminar on Standardisation of Drugs, organised by RGUHS, Karnataka.
Top