alexa Investigation Designed To Evaluate The Phytochemical And Pharmacological Activities Of Ethanolic Extract Of The Whole Plant Acalypha Indica Linn. In Experimental Animal Models
ISSN: 2167-0501

Biochemistry & Pharmacology: Open Access
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International Conference on Pharmacognosy, Phytochemistry & Natural Products
October 21-23, 2013 Radisson Blu Plaza Hotel, Hyderabad, India

Shivakumar Sidramappa Godipurge, JaiprakashSharanappa Biradara and Nitin Mahurkar
Posters: Biochem & Pharmacol
DOI: 10.4172/2167-0501.S1.003
Abstract
In the present study, phytochemical analysis of ethanolic extracts of the whole plant Acalypha indica L. (Euphorbiaceae) has indicated the presence of alkaloids, glycoside, steroid, flavonoids and terpenoid compounds. The use of this plant in traditional medicine, prompted us to check Acalypha indica L. for possible analgesic and anti-inflammatory activities. The ethanolic extract of Acalypha indica L. showed very good analgesic activity by employing Eddy?s hot plate and tail flick methods. A sustained and significant (P<0.001) inhibition of carrageenan-induced inflammation of rat paw observed with 200 and 400 mg/kg body weight. The ethanolic extract of Acalypha indica L. also demonstrated anti-inflammatory effect in a dose-dependent manner. Maximum inhibition by the extract was observed at 400 mg/kg body weight after three hours of ingestion, which was comparable to that of the standard drug diclofenac sodium at a dose of 25 mg/kg bodyweight.
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