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Investigations On Active Pharmaceutical Ingredient Crystal Growth And Comparative Study Of Properties | 7419
ISSN: 2167-7689

Pharmaceutical Regulatory Affairs: Open Access
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Investigations on active pharmaceutical ingredient crystal growth and comparative study of properties

2nd International Conference and Exhibition on Pharmaceutical Regulatory Affairs

Bhavani K Sankaranarayanan K and Jerome Das S

Posters: Pharmaceut Reg Affairs

DOI: 10.4172/2167-7689.S1.007

In pharmaceutics field many drugs are available in crystalline solid form for oral dosage due to its chemical stability, storage and easy handling. This paper deals the crystalline form of an Active Pharmaceutical Ingredients (API) of Paracetamol and Aspirin by slow evaporation technique using ethanol as a solvent to analyze and compare its physicochemical properties. Good quality of bio medical drug crystals was grown within three weeks and its stability was analyzed by thermal studies. The unit cell parameters of the grown crystals were determined by single crystal and powder X-Ray diffraction studies. Complete vibrational assignment of the various functional groups present in the crystalline drug substance was identified by FTIR studies. Optical and dielectric studies were also carried out to the grown crystals. It is found that both the APIs are crystallized well and it belongs to thermodynamically stable form of monoclinic system.
Ch. Teja is currently pursuing her 2nd year M. Pharmacy in Pharmaceutical Regulatory Affairs from JSS University, Mysore. She has done her graduation from the same college i.e. JSS College of Pharmacy, Mysore, Karnataka. She published 2 articles in reputed journals titled ?Comparative Study of In- Process and Finished Products Quality Control Tests of Indian Pharmacopoeia, British Pharmacopoeia & United States Pharmacopoeia for Capsules and Liquid Orals? and ?New Era in US Prescription Drug Labeling? Which was also presented as a poster in 63rd IPC. And also attended Indo- American Pharmaceutical Regulatory Symposium- 2011 and presented a poster on ?Indian Regulations on Cosmetics?.