alexa Is Leptospirosis A Disease That Attack Males More Than Females? | 70840
ISSN: 2471-9315

Applied Microbiology: Open Access
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12th International Congress on Microbial Interaction and Applications of Beneficial Microbes

Edmond Puca, Genti Stroni, Elda Qyra, Pellumb Pipero and Entela Y Puca
University Hospital Center - Mother Teresa, Albania
American Hospital, Albania
Posters & Accepted Abstracts: Appli Micro Open Access
DOI: 10.4172/2471-9315-C1-006
Abstract
Statement of Problem: Leptospirosis is a re-emerging zoonotic disease with global importance. It is a widespread and potentially fatal zoonosis that is endemic in many tropical regions and causes large epidemics after heavy rainfall and flooding. Human infection by leptospires has highly variable clinical manifestations, which range from subclinical infection to fulminant disease. Gender refers to the biological and physiological factors that define males and females, looks like to play an important role in the determination of the human leptospirosis. Purpose: The purpose of this study is to determine potential relationships of environmental context to human exposure to Leptospira. At the same time we want to analyze if any connection between human leptospirosis and the male or female gender exist, because traditionally, more male leptospirosis cases were observed in surveillance data has been explained through occupational /recreational exposures that put men in greater contact with Leptospira-infected animals or contaminated water. Methodology & Theoretical Orientation: For our ideas we did a search about human and animal leptospirosis studies. At the same time we did an observational study with human leptospirosis cases at the Service of Infectious Diseases, University Hospital Center, “Mother Teresa’’, Tirana, Albania. Findings: In most of the publications, we concluded that clinical cases with leptospirosis are males. Anyway same European studies have found that, while the incidence of leptospirosis is higher in men, there is no sex difference in leptospirosis seroprevalence so maybe biological and/or hormonal differences may play as a possible, alternative factor for the male excess in reported leptospirosis cases. Conclusion & Significance: Interpretations of dates from the observed sex/gender distributions from surveillance studies require careful thought, as there are important implications for public health actions. Male are more frequent presenting with clinical leptospirosis. More seroprevalence studies are needed to understand this connection or disconnection.
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