alexa Kaiso As Prognosis Marker Of Patients With Chronic Myeloid Leukemia
ISSN: 1948-5956

Journal of Cancer Science & Therapy
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Share This Page

Additional Info

Loading
Loading Please wait..
 

3rd World Congress on Cancer Science & Therapy
October 21-23, 2013 DoubleTree by Hilton Hotel San Francisco Airport, CA, USA

Jaime Cofre and Adhelay Eliana
ScientificTracks: J Cancer Sci Ther
DOI: 10.4172/1948-5956.S1.028
Abstract
Kaiso protein has been identified as a new member of the POZ-ZF subfamily of transcription factors that are involved in development and cancer. There is consistent evidence of the role of Kaiso and its involvement in human tumorigenesis but there is no evidence about its role in hematopoietic differentiation or establishment of chronic myeloid leukemia (CML). We used, normal K562 cell line, imatinib-resistant K562 cell line and bone marrow from patients in chronic and blastic phase of CML (CML-BP) to investigate the specific distribution of Kaiso and their role in the progression disease. Surprisingly our results suggest that cytoplasmic localization of Kaiso is related to a poor prognosis in patients with CML-BP.
Biography
Jaime Cofre, graduated in biology in the Pontifical Catholic University of Chile and received the Ph.D. in biophysics from the University Federal of the Rio de Janeiro, now is an Associate Professor of the embryology, head of the Molecular Embryology and Cancer Research Laboratory, Chairman of Education Board of Faculty of the Medicine at University Federal of Santa Catarina. He got his B.Sc. in Biology, M.Sc. in Molecular Biology and is a specialist in Molecular Embriology and Cancer. Currently his researches focus on the epigenetic machinery responsible for cancer and specifically on the role of non canonical wnt pathways and Kaiso/p120/cadherin as prognosis markers of cancer .
image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords