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Lipocalin-2 Mediates Hypertension Associated With Obesity | 50282
ISSN: 2155-9880

Journal of Clinical & Experimental Cardiology
Open Access

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Lipocalin-2 mediates hypertension associated with obesity

International Conference on Hypertension & Healthcare

Yu Wang

The University of Hong Kong, China

Posters & Accepted Abstracts: J Clin Exp Cardiolog

DOI: 10.4172/2155-9880.C1.042

Abstract
Obesity-associated hypertension is more difficult to control, due to the involvement of diversified mechanisms and multi-organ dysfunctions. Lipocalin-2 is an adipokine causatively contributes to obesity-induced endothelial dysfunction and hypertension. The present study investigated and compared lipocalin-2-mediated hypertension under both high fat diet and renin-angiotensinaldosterone system activation. The contribution of various sources of lipocalin-2 to the development of hypertension as well as the underlying mechanisms will be discussed here.
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