alexa Lissencephaly In Identical Twins - A Case Report
ISSN: 2161-0932

Gynecology & Obstetrics
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Share This Page

Additional Info

Loading
Loading Please wait..
 

2nd International Conference on Pediatrics & Gynecology-2012

P. Nagarjuna and H. Swamy Rajesh
Posters: J Pediatr Therapeut
DOI: 10.4172/2161-0665.S1.012
Abstract
Lissencephaly, which literally means smooth brain, is a rare brain formation disorder caused by defective neuronal migration during the early weeks of gestation, resulting in a lack of development of sulci and gyri. The final proper layer formation relies on an intricate balance between events of the cell cycle, proliferation, neuronal path findings and migration. The lissencephaly syndromes in humans involve abnormal cortical lamination and are categorized as neuronal migration defects. We report two cases of 10 year old, male identical twins, born to apparently healthy consanguineous parents with no significant antenatal, perinatal or immediate postnatal complications who were brought with complaints of delayed developmental milestones, mental retardation and seizures. Seizures were generalized tonic clonic type and started at 4 years of age in both the twins. Examination revealed microcephaly, mental retardation, hypertonia and spasticity with gait abnormality. In both the twins CT BRAIN revealed features of agyria ? pachygyria complex (lissencephaly) with dysmyelination changes. MRI BRAIN revealed : Classic type I lissencephaly with band heterotopia. The clinical features & neuroimaging studies are consistent with the findings of Type 1 Lissencephaly in both the identical twins. Key Words: Identical twins, seizures, lissencephaly
image PDF   |   image HTML
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords