alexa Longgu (Fossilia Ossis Mastodi, Dragon Bone) Changes The Component Profiles In Keishikaryukotsuboreito (Gui-Zhi-Jia-Long-Gu-Mu-Li-Tang)
ISSN: 2161-1459

Journal of Clinical & Experimental Pharmacology
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

5th International Conference and Exhibition on Pharmacology and Ethnopharmacology
March 23-25, 2017 Orlando, USA

Kazuki Oguri and Kyoko Takahashi
Osaka University, Japan
Posters & Accepted Abstracts: Clin Exp Pharmacol
DOI: 10.4172/2161-1459.C1.017
Abstract
Longgu (Ryu-kotsu, Fossilia Ossis Mastodii, Os Draconis, or dragon bone) is the only fossil crude drug listed in the Japanese Pharmacopoeia, which defined as “the ossified bone of large mammal." It is used as sedative component in Keishikaryukotsuboreito (KRB) formula in Kampo medicine (Traditional Japanese Medicine). In Japan, all longgu is purchased from People’s Republic of China. Longgu resources are facing the threat of depletion. Effective countermeasures are urgently required. However, information is insufficient about role of longgu in Kampo formulas. We investigated the significance of longgu in KRB formula, which comprises seven crude drugs. We analyzed the components in KRB decoction using inductively coupled plasma mass spectrometry and gas chromatography. Slight inorganic components and no organic ones were detected from single decoction of longgu. The organic component profile of KRB decoction is different from that of longgu-free KRB decoction. The result of scanning electron microscopy with energy dispersive X-ray spectroscopy showed that decocted longgu captured organic materials at its uneven surface with small pores. We hypothesized that longgu adsorbs the components on its surface. The decocted longgu were submitted into solid state NMR and nitrogen adsorption measurements. The results of them showed that KRB-decocted longgu had smaller water content and specific surface area than raw and single decocted longgu, respectively. These results supported our hypothesis. We suggest recycling of longgu as one of the countermeasure for depletion though development of purging methods is needed.
Biography

Kazuki Oguri is pursuing his PhD from Osaka University. He got a license for Japanese Pharmacist in 2013. His research focuses on longgu; one of the crude drugs used in Kampo medicine (Traditional Japanese Medicine). He has published three papers in journals.

Email: [email protected]

image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version