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In diabetes, retinal neurosensory dysfunction occurs earlier before any apparent retinal vascular changes are detected. The reports
on macular thickness in type 2 diabetics without retinopathy are inconsistent in terms of reporting thickness changes. Either there
was a decrease, an increase, or no change in thickness compared with healthy subjects. From a visual function perspective, diabetics
without retinopathy have shown visual dysfunction in some visual function tests, one of which is decreased contrast sensitivity at
high spatial frequencies under photopic and mesopic luminance conditions. Little is known, however, about the extent to which
contrast sensitivity is affected at low spatial frequencies in type 2 diabetics without retinopathy and its correlation with macular
thickness. The purpose of this study therefore was to assess the correlation between contrast sensitivity at low spatial frequencies
and macular thickness in type 2 diabetics without retinopathy and compare it with healthy subjects. The results showed a statistically
non-significant difference in contrast sensitivity between healthy subjects and type 2 diabetics without retinopathy at low spatial
frequencies. The central and the inner 3 mm macular subfield thicknesses were significantly thinner in the diabetics compared with
the healthy controls. In type 2 diabetics without retinopathy, the central macular subfield thickness was the only macular subfield
independently associated with contrast sensitivity at the spatial frequency of 0.5 cycles per degree. This presentation will further
discuss this correlation between macular thickness and contrast sensitivity in type 2 diabetics without retinopathy as an element for
future prediction of vision deterioration.
Shroug M Aldaham is a PhD candidate at the Complutense University of Madrid (UCM), Spain. She has a BSc in Optometry from King Saud University (KSU), Riyadh, Saudi Arabia, and a Master of Science in Vision Science from the University of Waterloo, Canada. She has joined the Optometry department at KSU as a Demonstrator (an academic position that prepares for professorship) before joining the Master program in Canada. After her Masters she returned to Riyadh and later joined the PhD program at UCM. Both of her Master and PhD studies were Saudi government-funded research grants.