Main Correlates Of Congenital Heart Defects | 50273
Journal of Clinical & Experimental Cardiology
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Aim: Enhancing knowledge towards main correlates and risk factors for congenital heart anomaly is important because of its high
mortality and morbidity. The present study aimed to assess main correlates of congenital heart defects in our population.
Methods: In a case-control study, 464 consecutive children with congenital heart defects confirmed on clinical manifestations as
well as complementary diagnostic tests such as echocardiography, CT scan or MRI were assessed. Also, 434 sex and age-matched
children without any evidences of congenital heart anomalies were included as the control. The study information was collected by
questionnaire which was filled by parents and physician in outpatients pediatric cardiology clinic.
Results: In the group with congenital heart defects, the most prevalent abnormality was VSD (33.6%), followed by PDA (20.3%) and
PS (20.1%). Regarding primary cardiac findings leading to diagnosis of heart defects, in addition to cardiac murmurs were found
chest pain in 0.9%, palpitation in 2.4%, dyspnea during activity in 2.3%, and cardiomegaly in 0.9%. Early diagnosis was based on
pediatrician in 56.0%, on general physician examination in 13.6%, and on doubt of parents in 2.7%. According to the multivariate
logistic regression modeling, main correlates of congenital heart defects included fatigue during breast feeding, fatigue during activity,
frequent colds, pulmonary disorders, obesity, history of abortion and consanguineous marriage. Also, breast feeding was adversely
correlated to congenital heart defects.
Conclusion: The main factors correlated to heart defects included fatigue during breast feeding and during activity, history of frequent
colds, various pulmonary disorders, obesity, history of abortion, and consanguineous marriage. In this regard, breast feeding could
predict lack of congenital heart defects.
Alireza Ahmadi has completed his Pediatric Specialist Board from Isfahan University and Pediatric Cardiology from Iran University in Tehran. He is a member of Isfahan Cardiovascular Research Center and Associate Professor of Isfahan Medical School. He has published more than 17 papers in reputed journals.