alexa Mapping Cardiac Progenitor Cell Fate Via The Mitochondria | 71641
ISSN: 2157-7552

Journal of Tissue Science & Engineering
Open Access

Like us on:

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

8th International Conference on Tissue Science and Regenerative Medicine

Sang-Bing Ong
Duke-NUS Medical School, Singapore
ScientificTracks Abstracts: J Tissue Sci Eng
DOI: 10.4172/2157-7552-C1-036
Abstract
Studies have documented that the adult heart contains a pool of CPCs that are clonogenic, self-renewing and multipotent. These cells are thought to exist in the heart to facilitate growth during adolescence and to provide a mechanism for minor repair and ongoing cell turnover within the adult heart. The CPCs have been shown to have therapeutic potential. To be effective in repairing the heart, the infused CPCs must successfully engraft, proliferate and differentiate into cells of the cardiac lineages. Although many studies have begun to investigate the signaling mechanisms involved in these processes, there are still significant gaps in our knowledge regarding the differentiation process of CPCs. Most importantly, little or no attention has been given to the alterations in mitochondria and redox status during differentiation of the CPCs. To transition from a non-contracting progenitor cell requiring little energy to a beating cardiac myocyte requires development of an energetic infrastructure that is capable of supporting the high metabolic demands of the myocyte. Thus, when a CPC commits to a myocyte lineage it must undergo substantial expansion, reprogramming and reorganization of its mitochondria, but how these processes are regulated in CPCs are currently unknown. This talk will shed light into the processes regulating mitochondrial maturation in CPCs during differentiation.
Biography

Sang-Bing Ong has completed his PhD at University College London, UK in the year 2010. He has then completed his Postdoctoral studies at University of California, USA in 2012. He has worked as an Adjunct Lecturer in Biomedical Engineering in Universiti Teknologi Malaysia till 2015. Currently he is working as an Assistant Professor under Cardiovascular and Metabolic Diseases Program in Duke-NUS Medical School, Singapore.

image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

bornova escort

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
Leave Your Message 24x7