alexa Microbial Metabolomics: New Biomarkers Describing Biological Mechanisms Related To M. Tuberculosis Growth, Virulence, Drug Resistance, And Host-microbe Adaptations/interactions
ISSN: 1948-5948

Journal of Microbial & Biochemical Technology
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Share This Page

Additional Info

Loading
Loading Please wait..
 

CO-ORGANIZED EVENT: International Conference on Chronic Diseases & 6th International Conference on Microbial Physiology and Genomics
August 31-September 01, 2017 Brussels, Belgium

Du Toit Loots
North-West University, Potchefstroom, South Africa
Posters & Accepted Abstracts: J Microb Biochem Technol
DOI: 10.4172/1948-5948-C1-029
Abstract
Statement of the Problem: Despite the fervent genomic and proteomic based research efforts to date, since its discovery in 1882, TB is still a major global problem, and hence new approaches are necessary to better characterize and diagnose this disease. One such strategy would be to investigate this from a metabolomics research perspective, in order to identify new metabolite markers better characterizing the disease. Methodology & Theoretical Orientation: A typical metabolomics workflow, including using semi-targeted and untargeted extraction procedures on cell cultures and patient collected sputum and urine, analysis on various LC-MS, GC-MS and NMR based approaches, followed by data clean-up and biomarker identification using various univariate and multivariate statistical approaches, was applied. Findings: The new TB biomarkers identified in the different sample material shed light on new metabolic pathways and mechanisms associated with growth, virulence, drug resistance, and host and microbe interactions/adaptations. Conclusion & Significance: Over the past 10 years, metabolomics has led to an exponentially increased number of new biomarkers identified, and subsequently rapid expansion of new knowledge and our understanding of various infectious diseases, including TB, which can ultimately be utilized towards improved diagnostics and treatment approaches.
image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords