alexa Micromeria Fruticosa (L.) Druce Ssp. Serpyllifolia: Constituents, Antimicrobial And Evaluation Of Burn Healing Activity Of The Extract And Its Isolated Active Constituents In Topical Formulation
ISSN: 2329-6631

Journal of Developing Drugs
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Share This Page

Additional Info

Loading
Loading Please wait..
 

International Conference and Exhibition on Pharmaceutical Development and Technology
April 24-26, 2017 Dubai, UAE

Naglaa G Shehab
Cairo University, Egypt
Dubai Pharmacy College, UAE
ScientificTracks Abstracts: J Develop Drugs Res
DOI: 10.4172/2329-6631-C1-023
Abstract
Micromeria fruticosa (L) Druce spp. serpyllifolia is widely used in the Mediterranean regions in treatment of various inflammatory conditions and in wound healing. The purpose of this study was to investigate the constituents of the ethanolic extract of Micromeria fruticosa (L.), to evaluate the antimicrobial and the burn healing activities of the extract, its fractions and its isolated compounds and to formulate, characterize and evaluate natural burn-healing topical preparations containing the crude plant extract or the isolated compounds. The LD50 of the ethanolic extract (up to 4 g/kg) indicated its safety. The growth inhibitory activity of the ethanolic extract, and its hexane, chloroform, and n-butanol fractions as well the isolated compounds was evaluated in-vitro against a set of micro-organisms. The isolated compounds from the chloroform and n-butanol fractions were belonging to flavonoids and triterpenes. The ethanolic extract as well its fractions, hexane, chloroform and butanol exhibited variable antimicrobial activities comparable to broad spectrum antibiotic gentamycin used as control. These effects could be attributed to the isolated flavonoids and triterpenes compounds. Burn healing potentiality of the ethanolic extract was also explored against the commercial product and found noticeably significant. Histopathological analysis showed sever endodermal, columnar basal cells and sebaceous gland damage in the untreated burnt animals whereas treated animals showed significant reduction in wound size and improvement in the histological finding. Besides, from the in vivo burn healing and histological results, the topical formulae enhanced the skin wound re-epithelialization and speeded up the healing process.
Biography

Naglaa G Shehab is an Associate Professor at the Pharmaceutical Chemistry and Natural Products Department, Dubai Pharmacy College, Dubai, UAE. She graduated from Faculty of Pharmacy, Cairo University, Egypt and received the PhD from the same college. She is a member of American Society of Pharmacognosy and Italo-Latin American Society of Ethnomedicine and serving as an Editorial Board Member in Natural Products Chemistry and Research. Also, she is a reviewer for many international journals concerning chemistry and biological activity of medicinal plants. She published at least 30 scientific papers also contributed in publication of a scientific book and her field of interest is bioactivity of medicinal plants.

Email: [email protected]

image PDF   |   image HTML
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]icsonline.com

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords