alexa Micronucleus In Exfoliated Buccal Mucosa Cells Of Mexican Women With Breast Cancer
ISSN: 1948-5956

Journal of Cancer Science & Therapy
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Share This Page

Additional Info

Loading
Loading Please wait..
 

3rd World Congress on Cancer Science & Therapy
October 21-23, 2013 DoubleTree by Hilton Hotel San Francisco Airport, CA, USA

Aurelio Flores-Garc?a1, Jes?s Salvador Velarde-F?lix, H?ctor Rangel-Villalobos, Eloy Alfonso Zepeda-Carrillo, Amelia Rodr?guez-Trejo, Pedro Agu?ar-Garc?a and Olivia Torres-Bugar?n
ScientificTracks: J Cancer Sci Ther
DOI: 10.4172/1948-5956.S1.028
Abstract
Breast cancer is the most frequently diagnosed form of cancer and the leading cause of cancer death among females in the world.Increased number of micronucleus (MN) in exfoliated buccal mucosa cells (BMC) of patients with primary breast, lung and cervix uteri cancer has been observed compared to control subjects.Micronucleus (MN)originates from chromosomal fragments and/or whole chromosomes that are not included in the main daughter nuclei during nuclear division.MN frequency in BMCof Mexican women with primary breast cancer was evaluated in this study, including30 never-treated cancer patientsfrom the State Center of Cancer of Nayarit,and 60 females in the control group. Average age of participants was(49.50?14.12 and 50.35?10.24 yearsfor cancer patientsandcontrol subjects respectively). They signed an informed consent andwere asked to complete a questionnaire concerning smoking habits, alcohol consumption, health status,diet andconsumption of drugs or antioxidants. BMC were collected from both cheeks ineach subject. Smears were air-dried, fixedin 80% ethanoland stained with acridineorange. Micronucleated cells (MNCs) were counted in 2,000 cells at 100? magnificationusing amicroscopeepifluorescence. MNCs were scoredaccording to the criteria established by Tolbert and the criteria recently described by Ceppi.Analysis of the data using theMann-Whitney U-test showed significant increase ofMNCsnumber in breast cancer patientscompared to control subjects (p<0.0001). Cancer patients presented 1.67?1.15 (0-4, rank) MN, and 0.80?0.63 (0-2, rank)MN in control subjects. In conclusion, a genotoxic damage was observed in BMC of Mexican women with breast cancer.
Biography
Aurelio Flores-Garc?a obtained his Ph.D. in Immunology from the University of Guadalajara. He is currently a Professor and Researcher at the Autonomous University of Nayarit School of Medicine.
image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords