alexa Minimum Duration Of Antibiotics Based On Blood Culture In Ruled Out Neonatal Sepsis | 63947
ISSN: 2161-0665

Pediatrics & Therapeutics
Open Access

Like us on:

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

10th Annual World Congress on Pediatrics,Pediatric Gastroenterology & Nutrition

Naveed Durrani, Niels Rochow, Jameel Alghamdi and Sourabh Dutta
McMaster Children Hospital, Canada
Posters & Accepted Abstracts: Pediat Therapeut
DOI: 10.4172/2161-0665.C1.037
Abstract
Background & Objective: In NICU, blood culture is monitored at least 48 hours before stopping antibiotic treatment in rule out sepsis. The objective of the study is to analyze the time to positive blood cultures for rule out sepsis to estimate minimum duration of antibiotics needed. Methods: Retrospective observational study was performed in NICU at McMaster Children hospital (January 2004 to December 2013). Positive blood cultures identified with BacT/Alert ®3D microbial detection system were analyzed for all admitted newborns. Outcome parameter were microorganisms, hours from inoculation to positive blood culture, age at the time of culture taken. Time to positivity was evaluated for clinically important gram positive and gram negative bacteria and yeast. Results: In 9254 babies, 7480 blood cultures were performed. 845 (11.3%) were positive for organisms. 815 (96%) were considered as significant organism causing disease in newborn (yeast, definite, possible pathogens) while 30 (4%) had contaminants. 54 (6.4%) blood cultures were positive in EOS (Early onset sepsis in <72 hours of age) while 791 (94%) were in LOS (late onset sepsis >72 hours of age). 613 (72.5%), 802 (95%) and 43 (5%) blood cultures turned positive by 24hr, 48hr and > 48hrs of incubation respectively. All gram-negative organisms in EOS and LOS were identified within 24 hours except one at 26 hours. Conclusion: Probability of gram negative microorganisms growing beyond 24 hours is small. Initial antimicrobials treatment can be reduced after 24 hours to target only gram positive organism beyond 24 hours in LOS, while they may be stopped in EOS unless clinically indicated.
Biography

Naveed Durrani did his Post-graduation in Pediatrics from Pakistan in 2004 and MRCP from Royal College of Physicians of Ireland in 2009. Currently, he is doing his fellowship in Neonatal-Perinatal Medicine at McMaster University, Canada. His interest is in neonatal sepsis and various quality improvement projects. He has more than 10 publications in an index medical journal.

Email: [email protected]

image PDF   |   image HTML
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
Leave Your Message 24x7