Reach Us +441474556909
Monoclonal Antibodies Against Common Salivary Protein 1 | 2731
ISSN: 2155-6210

Journal of Biosensors & Bioelectronics
Open Access

Like us on:

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Monoclonal Antibodies against Common Salivary Protein 1

International Conference and Exhibition on Biosensors & Bioelectronics

Hong-Tao Wang, Stephanie Ho, Eun-Seon Yoon and Eui-Yul Choi

Posters: J Biosens Bioelectron

DOI: 10.4172/2155-6210.S1.13

Backgroud: Saliva is mainly secreted by three pairs of salivary glands (parotid gland, sublingual gland and submandibular gland) and flows into oral cavity through ducts. Saliva contains around 100~140 kinds of protein, and common salivary protein 1(CSP1) is one of them. Methods: Here the recombinant CSP1 (rCSP1) was expressed and purified with GST agarose resin. The purified rCSP1 was used to immunize mouse to produce monoclonal antibodies (MAbs). Results: The CSP1 in saliva was identified as one form which size was about 25kDa with MAbs. Immunohistochemical assay showed that the CSP1 was specifically localized in salivary glands rather than other organs including exocrine glands such as pancreas, prostate, adrenal, and thyroid. The mean concentration of CSP1 in saliva is 19.6 (11.7) μg/ml, which may show some correlation between the concentration of CSP1 and the possibility of developing dental caries. Conclusion: The monoclonal antibodies were successfully made and could be used to identify that CSP1 was exclusively localized in salivary glands.
Relevant Topics