alexa Multivariate Analysis Of Factors Associated With The Koebner Phenomenon In Vitiligo: An Observational Study Of 381 Patients | 66785
ISSN: 2155-9554

Journal of Clinical & Experimental Dermatology Research
Open Access

Like us on:

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

14th International Conference on Clinical and Experimental Dermatology

Huma Khurram
King Saud University, Saudi Arabia
Posters & Accepted Abstracts: J Clin Exp Dermatol Res
DOI: 10.4172/2155-9554-C1-060
Abstract
Background: The Koebner phenomenon (KP) is a common entity observed in dermatological disorders. The reported incidence of KP in vitiligo varies widely. Aim: To estimate the prevalence of KP in vitiligo patients and to establish different associations between KP and vitiligo characteristics. Methods: A cross-sectional observational study was conducted using 381 vitiligo patients. Demographic and clinical information was obtained via the completion of Vitiligo European Task Force (VETF) questionnaires. Patients with positive history of KP were extracted from this vitiligo database. Multivariate analysis was performed to assess associations with KP. Result: The median age of cases was 23 years (range=0.6-76). In total, 237 of the patients were male (62.2%). Vitiligo vulgaris was the most common type observed (152/381, 40%). 72% (274/381) patients did not exhibit KP, whereas 28.1% (107/381) of patients exhibited this condition. Age (p=0.019), BSA% (p<0.001) and disease duration (p=0.011) were significantly increased in cases with KP compared with cases without KP. Family history of vitiligo, leukotrichia, halo nevi and premature grey hair were not significantly associated (p>0.05) with KP. KP was more common in males 64/107 (59.8%, p=0.004). Progressive disease (OR = 1.82, CI (1.17 – 2.92), p=0.041), > 5 years disease duration (OR = 1.92, CI (1.22 – 2.11), p=0.003) and BSA > 2% (OR = 2.20, CI (1.26 – 3.24), p<0.001) were significantly associated with positive KP. Conclusion: Our results suggest that KP may be used to evaluate disease activity and investigate different associations between the clinical profile and course of vitiligo. Future studies are needed to predict the relationship between KP and responsiveness to therapy.
Biography

Email: [email protected]

image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

+1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
Leave Your Message 24x7