alexa Myo-inositol In Thyroid Autoimmune Disorders
ISSN: 2161-0509

Journal of Nutritional Disorders & Therapy
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Share This Page

Additional Info

Loading
Loading Please wait..
 

JOINT EVENT: 13th International Congress on Advances in Natural Medicines Nutraceuticals & Neurocognition & 14th International Conference on Clinical Nutrition
July 27-29, 2017 Rome, Italy

Silvia Martina Ferrari, Alessandro Antonelli and Poupak Fallahi
University of Pisa, Italy
ScientificTracks Abstracts: J Nutr Disorders Ther
DOI: 10.4172/2161-0509-C1-006
Abstract
Myo-inositol has a determinant role in different metabolic pathways. Experimental data and clinical trials showed that myo-inositol and phosphatidylinositol(s) are involved in physiological and pathological conditions of the thyroid. Phosphatidylinositol is important in the intracellular signaling associated with thyroid-stimulating hormone (TSH) pathway in thyrocytes, and it is involved in thyroid autoimmunity. Recently it has been demonstrated the beneficial effects obtained by myo-inositol in association with seleno-methionine in patients affected by subclinical hypothyroidism. The myo-inositol effectiveness on TSH could be explained by its biological role in the TSH hormone signaling, as inositol regulates the H2O2- mediated iodination and the impairment of inositol-depended TSH signaling pathway can cause TSH resistance, and hypothyroidism. For this reason, the therapy can increase the amount of the second messenger, improving the TSH sensitivity. Moreover, it seems that myo-inositol could have promising therapeutic effects in insulin resistance, metabolic syndrome and their related disorders [diabetes, polycystic ovary syndrome (PCOS)], autoimmunity and certain malignancies, and their links. Further studies on the inositol pathways involved in certain disorders could lead to hypothesize additional therapeutic applications.
Biography

Silvia Martina Ferrari graduated in Biological Sciences cum laude in 2002 and specialized in Clinical Pathology in 2007 at the University of Pisa (Italy). Her principal areas of expertise are autoimmune thyroid disorders, chemokines and cytokines, type 1 diabetes, systemic autoimmune disorders, HCV-associated thyroid disorders and thyroid cancer. Her researches have been published in more than 140 articles in international journals (HI=37). She serves as an Editorial Board Member and is Referee and Reviewer of many scientific international journals.

image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords