Nanoparticles And Drug Delivery Applications | 2732
Journal of Biosensors & Bioelectronics
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Nanoparticles are widely used because of their unique tunable properties and application in various fields of science and
technology. Among other nanoparticles the Iron oxide nanoparticles are extensively being employed in various biomedical
applications including MRI (Magnetic Resonance Imaging), magnetic separation, magnetically induced hyperthermia, and drug
delivery. The important properties of magnetic iron oxide particles for medical applications are non-toxicity, biocompatibility,
injectability, and high-level accumulation in the target tissue or organ; Iron oxide is also widely used because of its magnetic
nature and that allows the movement of the drug delivery system to desired target site with an external magnetic field. Drug
delivery through magnetic carrying systems are of particular interest in cancer therapy where the side-effects are severe and the
amount of drug that must be ingested is increased due to the minute amount that reaches the tumor with each dosage. The main
challenge in this research field is to improve the magnetic nanoparticles drug carrying capacity. Various methods of synthesis of
magnetic nanoparticles and their drug loading & release profiles are discussed. This presentation also covers the other biomedical
applications of other nanoparticles such as CaCO3 nanoparticles obtained from renewable resources such as eggshell and ZnO,
TiO2, Ag, CNTs, and their hybrid nanoparticles.
Vijaya K Rangari is an Associate professor at Department of Materials Science and Engineering, Tuskegee University. Dr.Rangari has received his Ph.D in 1996 from Osmania University, India and a post doc at Indian Institute of Science, Bangalore India and Bar-Ilan University, Israel. Dr.Rangari?s main research interests are: a) Synthesis of various types of nanoparticles with different surface chemistries, shapes and sizes using CVD, sonochemical and microwave techniques; and b) Alignment of acicular nanoparticles in polymeric fibers through single screw melts extrusion for multifunctional textile applications. c) Applications of magnetic and bio-based nanoparticles for medical applications. He has published about 70 research articles in reputed journals, 80 conference proceedings and 3 chapter books.
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