Nanoshell plasmons are a novel type of composite spherical nanoparticles consisting of a dielectric core covered by a thin
metallic shell which is typically gold. Nanoshells possess highly favorable optical and chemical properties for biomedical
imaging and cancer treatment. By varying the relative dimensions of the core and shell the optical resonance of these nanoparticles
can be precisely and systematically varied over a broad region ranging from the near U.V to the mid IR. This review article
includes the synthesis and properties of gold nanoshells, transport mechanisms of nanoshells in to tumors and illustrate how
the core/shell ratio and overall size of a nanoshell influences its scattering and absorption properties, and also describes several
examples of nanoshell based diagnostic and therapeutic approaches including the development of nanoshell bioconjugates for
molecular imaging, the use of scattering nanoshells as contrast agents for optical coherence tomography (OCT), and the use of
absorbing nanoshells in NIR thermal therapy of tumors.
P. Spoorthy had completed B.Pharmacy from Vignan institute of pharmaceutical sciences. She is pursuing M.Pharmacy in Gokaraju Rangaraju
College of Pharmacy.
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