alexa Nanotechnology: Formulation, Scale-up And CGMP Manufacture For Clinical Investigation
ISSN: 2157-7439

Journal of Nanomedicine & Nanotechnology
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Share This Page

Additional Info

Loading
Loading Please wait..
 

4th International Conference on Nanotek & Expo
December 01-03, 2014 DoubleTree by Hilton Hotel San Francisco Airport, USA

Mostafa Nakach and Jean-Ren? Authelin
Accepted Abstracts: J Nanomed Nanotechnol
DOI: 10.4172/2157-7439.S1.019
Abstract
Recently research work in the field of parenteral nanotechnologies has shown that many nano-objects of therapeutic interest, including (nano-crystalline suspension, emulsion, liposomes, polymeric nano-particles) can be manufactured using high pressure homogenization. Most of these studies however are focused on exploratory research activities. Amongst the hurdles to test these nano-objects in a clinical research setting and eventually reach the market are the design of stable commercial formulation, process scale-up and cGMP manufacturing in aseptic environment. Sanofi has developed a unique technology platform to support the formulation, manufacture and supply of nanotechnology based projects from preclinical, through clinical to industrialization and launch. In the present communication the author will focus on the presentation of 3 key areas of this platform: ? A physico-chemical based approach to formulation and process engineering ? Process development and scale-up ? Parenteral cGMP pilot facilities designed to accommodate highly active product, and operate at high pressure and high temperature. This pilot line is able to supply batches from hundreds of grams to a few kilogrammes of nano-crystalline suspension, nano-emulsion or liposomes.
Biography
Mostafa Nakach is a Pharmaceutical Engineer from Ecole des Mines d?Albi and a Master 2 graduate from Paris-sud 11 University in Pharmacotechnie and Biopharmacy. He is working within Sanofi group since 26 years. His current position is Head of Pharmaceutical Engineering section within pharmaceutical science operations. His mission is to build and to manage the required skills and capabilities in order to support R&D projects development. He also worked as API physical quality research engineer within chemical development department. His mission was focused on the process development of solid chain: from crystallization to particles engineering.
image PDF   |   image HTML
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords