alexa Narrow Band-ultraviolet B And Psoralen Plus Ultraviolet A In Mycosis Fungoides Therapy: A Retrospective Study
ISSN: 2155-9554

Journal of Clinical & Experimental Dermatology Research
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11th Global Dermatologists Congress
November 14-15, 2016 Dubai, UAE

Mehmet Unal
Konya Numune Hospital, Turkey
Posters & Accepted Abstracts: J Clin Exp Dermatol Res
DOI: 10.4172/2155-9554.C1.045
Abstract
Statement of the Problem: The efficiency of narrowband ultraviolet B (NB-UVB) and psoralen plus ultraviolet A (PUVA) in treatment of mycosis fungoides (MF) was evaluated. Methodology & Theoretical Orientation: 61 patients diagnosed with MF treated with NBUVB or PUVA were studied retrospectively. Gender, age, time of diagnose, duration from initial lesion/lesions to diagnose and treatment, lypmhadenopathy, MF stage, phototherapy regime, systemic agents, mean time to complete remission (CR), mean number of treatment to CR, mean irradiation dose to CR, mean duration of maintenance therapy, mean relapse-free interval, relapse rate, total follow-up duration, adverse effects during treatment and comorbidities obtained from patients dermatological charts were recorded. Findings: Our results indicate that NB-UVB and PUVA have similar conclusions in treatment of early-stage MF. Mean-time to CR and mean duration from CR to relapse was shorter for patients who treated with NB-UVB than PUVA group. CR rate was lower in stage 2A. Combination of systemic agents with phototherapy did not have a statistically significant impact as expected. Conclusion: At the end of our study, we observed that NB-UVB and PUVA are useful and have acceptably good results in patients with early-stage MF. Mean-time to CR and mean duration from CR to relapse was shorter for NB-UVB group.
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