alexa Network Medicine: Metabolomics And Personalized Medicine In Neonatal Pathologies And In Some Neurological Disease
ISSN: 0975-0851

Journal of Bioequivalence & Bioavailability
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Share This Page

Additional Info

Loading
Loading Please wait..
 

5th World Congress on Bioavailability and Bioequivalence Pharmaceutical R&D Summit
September 29-October 01, 2014 DoubleTree by Hilton Baltimore-BWI Airport, USA

Luigi Barberini
Accepted Abstracts: J Bioequiv Availab
DOI: 10.4172/0975-0851.S1.019
Abstract
T his presentation is about the quantification of urinary metabolites and network model of interaction between metabolites defining the named ?network medicine? a network-based approach to human disease. The author will discuss about an innovative application of a supervised multivariate analysis with data filtered with Orthogonal Signal Correction (OSC), a filtering technique applied to introduce in the model the metabolome alteration related to a primary macroscopic classification of pathological condition. The author will also discuss the application of the network medicine to the urinary metabolome in autism spectrum disorders ASD patients and the neonatal urinary metabolome in newborn defined IUGR (intrauterine growth retardation) and newborn Large for Gestational Age LGA. This method had the ability to point out the connection between peripheral processes that can be originated in endocrine system as well in immunology and digestive systems and may be related to the uro-nephrological, neurologic, and cardiovascular system. A disease rarely can be considered as a direct and univocal consequence of genes abnormalities; it reflects the perturbations of the complex intracellular and intercellular network that links tissue and organ systems between them and to the environment. Metabolomics as emerging tools of network medicine, offer a platform to explore systematically the molecular complexity of a particular disease, leading to the identification of disease modules and pathways, but also the molecular relationships among apparently distinct (patho) phenotypes related to external perturbations. In this way there exists a connection between all the ?omic? platforms to better investigate pathologies with elevated social importance
Biography
Luigi Barberini after his degree in Physics from University ?La Sapienza? in Rome moved to Cagliari, (Italy) and received a PhD in Chemical-Physics and then specialization in Medical Physics. He is a Technical Officer at Cagliari University, coordinator of the UASB research unit for analysis of biological signals and images. He has published more than 45 papers in international peer-reviewed journals and has been serving as an editorial board member of repute journals. He introduced and developed the metabolomics studies at the University of Cagliari in 2003, with a multidisciplinary Clinical Project. He receives funds for the installation of the first NMR spectrometer dedicated to clinical metabolomics in Cagliari. He has coordinated clinical research projects in Neurology, Forensic Medicine, Toxicology, Cardiology and Neonatology.
image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords