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|University of Greenwich, UK|
|Keynote: Pharmaceut Reg Affairs|
|For thousands of years, mankind has used nature as a source of medicine. Despite the tremendous advances in medicinal chemistry and/or drug discovery areas over the years, our modern pharmacy even today employs a significant number of drugs that trace their origin back to natural products. Inflammatory diseases, especially chronic disorders such as arthritis, inflammatory bowel disease, psoriasis, sepsis, etc., continue to be a burden to large number of people and national health services throughout the world. With the severe limitations of the existing anti-inflammatory drugs (e.g. cost, side effects and efficacy) for such diseases, the appetite for novel drugs is as great as ever. During the past three decades, our researches have been mainly focusing on the identification of novel pharmacologically active compounds from medicinal plants. By using the bioassay-guided isolation approach, we have identified numerous compounds that showed potential in the various experimental models. In this communication, case examples are presented where the anti-inflammatory potential of crude and purified natural products have been validated through cell-free, cell-based and animal models of inflammation.|
Solomon Habtemariam has completed his PhD, 2 years of Post-doctoral Research (Strathclyde Institute for Drug Research) and 4 years of Lectureship at Strathclyde University. Since then, he has been a leader of researches on bioassays & natural products-based drug development at the University of Greenwich and Founder/Owner of Herbal Analysis Services. He is an Elected Fellow of the Royal Society of Medicine, the Royal Society of Chemistry, the African Academic Institute and the African Academy of Sciences. He has published over 130 papers in peer reviewed journals and has been serving as an Editorial Board Member for many journals.
Email: [email protected]
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