alexa NOACS-Novel Oral Anticoagulants: Are We There Yet? | 19889
ISSN: 2155-9864

Journal of Blood Disorders & Transfusion
Open Access

Like us on:

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

2nd International Conference on Hematology & Blood Disorders

Helen Philippou
ScientificTracks Abstracts: J Blood Disorders Transf
DOI: 10.4172/2155-9864.S1.006
Abstract
Thrombosis results in 25,000 and 200,000 fatalities from venous and arterial thrombosis, respectively, annually in the UK alone. Hitherto, anticoagulants are used to prevent stroke in patients with atrial fibrillation (AF), and to prevent deep venous thrombosis and pulmonary embolism in medical or surgical patients. However current anticoagulant treatments are associated with a significant risk of bleeding. There is an urgent clinical need for safe, effective anticoagulant therapies which prevents thrombotic events without causing the significant bleeding side-effects of currently available treatments. Warfarin has for some time been the standard anticoagulant treatment approved for widespread clinical use but is associated with many problems including a significant risk of bleeding and the need for careful laboratory monitoring regularly to achieve dosing of the drug within the therapeutic dose range. New oral agents have recently been approved for long term use (a direct thrombin inhibitor, dabigatran, and activated factor X (FXa) inhibitors, rivaroxaban and apixaban). These newer drugs address some of the clinical shortcomings of warfarin, most important of which is that the requirement to monitor and adjust the treatment dose is obviated. However, significant major and minor bleeding risks remain associated with these new agents. This work will discuss the attributes of an ?ideal? anticoagulant and where we need to focus our attention if we are to address the major unmet clinical need of current anticoagulation therapy.
Biography
Helen Philippou completed her PhD in 1997, from the University of London (Charing Cross and Westminster Medical School), UK and immediately obtained a tenured post at Imperial College, London, UK followed by the University of Leeds, UK, where she is an Associate Professor. She is Academic Theme Lead of Translational Cardiovascular Research, at the University of Leeds. She is also the current Chairman of the FXIII and Fibrinogen Subcommittee of the International Society of Thrombosis and Haemostasis.
image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

+1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version