alexa Occurrence Of Metallo-β-lactamase In Clinical Isolates Of Escherichia Coli And Klebsiella Pneumoniae
ISSN: 2161-0703

Journal of Medical Microbiology & Diagnosis
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Share This Page

Additional Info

Loading Please wait..

International Conference on Medical and Clinical Microbiology
July 03-04, 2017 Bangkok, Thailand

Krishus Nepal
Tribhuvan University, Nepal
Posters & Accepted Abstracts: J Med Microb Diagn
DOI: 10.4172/2161-0703-C1-009
Resistance mediated by Metallo-β-Lactamases (MBL) enzyme to broad spectrum antibiotics is an increasing global problem. The member of Enterobacteriaceae producing MBL, particularly in E. coli and K. pneumoniae constitutes a serious threat to current β-lactam therapy. Therefore, this study was conducted to know the occurrence of MBL producer in the clinical isolates of E. coli and K. pneumoniae. This was a descriptive cross sectional study conducted at OM Hospital and Research Centre (P) Ltd., Chabahil, Kathmandu, Nepal between May and December 2015. A total of 177 non-duplicate, consecutive isolates of E. coli (n=138) and K. pneumoniae (n=39) were isolated from different clinical samples. Of the total 177 isolates, 7 (4%) and 61 (34.5%) isolates were MBL and ESBL producer respectively. The co-existence of ESBL and MBL within the same isolates was not observed. MBL producing isolates showed high resistance to both β-Lactam and non-β-Lactam antibiotics used; entire MBL producers were Multi Drug Resistant (MDR). Of the drug used in the study, Colistin was only found effective for the treatment of MBL producing isolates. Our finding showed considerable number of MBL producing E. coli and K. pneumoniae isolates with MDR. Thus, it would be important for the early detection of MBL producing isolates for establishing potent antibiotics therapy which will be fruitful for controlling infection and also to avoid circulation of such strains within the hospital.

Email: [email protected]

image PDF   |   image HTML

Relevant Topics

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version