alexa One Health (OH) Concept On The Assessment Of In Vivo Antiparasitic Activity Of Nerolidol Against The Growth And Survival Of Zoonotic Haemoflagellate Protozoa, Trypanosoma Evansi | 72179
ISSN: 2157-7579

Journal of Veterinary Science & Technology
Open Access

Like us on:

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

7th International Veterinary Congress

Mohd Shukri Baba and Zainal Abidin Abu Hassan
Kulliyyah of Allied Health Sciences – IIUM, Malaysia
ScientificTracks Abstracts: J Vet Sci Technol
DOI: 10.4172/2157-7579-C1-024
Abstract
The concept of One Health (OH) emphasizes on how the involvement of multidisciplinary careers can be jointly approached to ensure the safety and health of humans and animals, as well as to maintain the environmental sustainability. Towards the end of this study, the authors demonstrated how the manipulation of bioactive compound namely nerolidol or 3,7,11-trimethyl-1,6,10- dodecatrien-3-ol (C12H26O), extracted from the seed of natural planted spice, Eiettaria cardamomum (cardamom), promisingly can solve the endemicity of vector-borne zoonotic manifestation of trypanosomiasis. By assessing the cell morphological changes and toxicity assessment of blood enzymes and vital organs, nerolidol was compared with Berenil (C18H22N8O3) on the growth and survival of the animal haemoflagellate protozoa Trypanosoma evansi. Groups of male ICR strain mice (6–8 weeks old, 20–25 g body weight) were intraperitoneally (i.p) infected with the parasite at 5.0×103 T. evansi per mouse and orally given pre-, concurrent- and postinfection treatments with 0.1 ml of nerolidol at 10 μg/ml per mouse. By using Giemsa stained blood slides and examined under the light and scanning electron microscopes (SEM), there was a positive correlation (p≤0.05, n=6) between the mice survival time and the ability to inhibit the parasites growth in pre-infection treatment group. The mice in this group was also recorded the longest prepatent (42.19±1.2 days) and survival (264.58±0.6 days) period. The morphological changes of T. evansi cells were observed where the undulating membrane was destroyed other than the cell became crescent-shaped and both of the posterior and anterior ends were tapered before the flagellum disintegrated in which lead to death of the cells. Besides, the results for biochemical tests were positively situated in the normal ranged level as well as no abnormalities found on the selected vital organs. This study significantly evidenced that nerolidol could be manipulated for the preservation and welfare of human beings, animals and environment. Thus, it is suggested that the scientists and practitioners from many disciplines needs to initiate to work collaboratively to synthesize and develop the novel solutions towards the trypanosomiasis which was problematize to the policy makers and people who deal with human and veterinary medicine.
Biography

Mohd Shukri Baba has his expertise in parasitology and animal health, as well as enhancing the natural products and endophyte Streptomyces-derivative compounds for curing many zoonotic diseases in improving the health and wellbeing of both human and livestock. As a member of Malaysian Society of Parasitology and Tropical Medicine, he was frequently being invited both locally and internationally as a speaker in many relevant conferences focusing on One Health concept which emphasizes on how the involvement of multidisciplinary careers can be synergistically approached to ensure the safety and health of humans and animals, as well as to maintain the environmental sustainability. Besides, he was also on his track of patenting one promising novel compound for antimalarial drug towards zoonotic simian malarial agent, Plasmodium knowlesi. Latest, he was appointed as Head of Biomedical Science Degree Program in International Islamic University Malaysia, as well as a main reviewer for Biomedical Science degree profession in Malaysia.

image PDF   |   image HTML
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

kactakapaniyor.com

[email protected]

+1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

Taktube

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

porn sex

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

Gaziantep Escort

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

sikiş

[email protected]

1-702-714-7001Extn: 9037

instafollowers

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

mp3 indir

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

putlockers

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

seks

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version