alexa Paclitaxel Loaded Cationic Solid Lipid Nanoparticle Formulation, Preparation And Evaluation | 24476
ISSN: 2157-7439

Journal of Nanomedicine & Nanotechnology
Open Access

Like us on:

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

4th International Conference on Nanotek & Expo

Ahmet Alper Ozturk, Behiye Senel, Evrim Yenilmez, Ebru Basaran and Gulay Buyukkoroglu
Posters: J Nanomed Nanotechnol
DOI: 10.4172/2157-7439.S1.018
Abstract
Now a days one of the most important health problem is cancer which is characterized by uncontrolled cellular proliferation. Paclitaxel is a mitotic inhibitor used in cancer chemotherapy; it represent the taxane family of drugs. Paclitaxel?s mechanism of action involves its stabilization of cellular microtubules; as a result, it interferes with the normal breakdown of microtubules during cell division. It is effect on the proliferation of tumor cells suppression with by prevent the vascularisation (angiogenesis), cell migration and collagen formation. Therefore, Paclitaxel is used commonly for treatment of lung, ovarian, breast, and head and neck cancers in therapy. Solid lipid nanoparticles (SLNs) were introduced at the beginning of the 1990?s as an alternative to traditional delivery systems such as emulsions, liposomes and polymeric systems. SLNs are nano-sized particles prepared using lipids which are solid at room and body temperatures and which can be stabilized with surfactants. The lipids used are biocompatible compounds with GRAS feature. The objective of this study was to formulate biodegradable and biocompatible cationic lipid delivery systems which is loaded Paclitaxel. After evaluation of the particle size, surface charge and the degree of crystallinity of formulation, cell culture studies were performed for the determination of cytotoxic effects. Colorimetric MTT method was used for the quantitative determination of cell cytotoxicity and MDA and MCF-7 cells were used.
Biography
Ahmet Alper Ozturk got Bachelor?s degree in 2013/June from Anadolu University, Faculty of Pharmacy. He started his PhD programme in 2013/September. Since 2014 he has been working as a Research Assistant at the Department of Pharmaceutical Technology at Anadolu University. He has participated practical studies of ?Vitamin C loaded liposome formulation and characterization? by ERASMUS Internship Program at University of Cagliari (Italy) in 2011.
image PDF   |   image HTML
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

kactakapaniyor.com

[email protected]

+1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

Taktube

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

porn sex

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

Gaziantep Escort

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

sikiş

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

https://www.gaziantepescort.info

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

mp3 indir

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

putlockers

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

seks

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version