alexa Pharmaceutical Standardization- Safety, Efficacy And Pharmacokinetic Evaluation Of A Traditional Unani Formulation: Jawarish-e-bisbasa
ISSN: 2327-5162

Alternative & Integrative Medicine
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International Conference and Exhibition on Traditional & Alternative Medicine
December 09-11, 2013 Radisson Blu Plaza Hotel, Hyderabad, India

Sunita Shailajan
Accepted Abstracts: Altern Integ Med
DOI: 10.4172/2327-5162.S1.004
Abstract
Jawarish-e-Bisbasa ; a Unani formulation, is prescribed for the clinical treatment of a wide range of gastrointestinal disorders. Though the formula composition and therapeutic claims of Jawarish-e-Bisbasa are part of National Formulary of Unani Medicine, the scientific methods for its quality, safety and efficacy are yet to be documented. Hence, this study is an attempt to develop some quality control tools for Jawarish-e-Bisbasa . SOPs for the preparation of Jawarish-e-Bisbasa was developed by the amalgamation of traditional methods and scientific tools. Preliminary phytochemical and physicochemical evaluation of Jawarish-e-Bisbasa was carried out. Chromatographic standardization of Jawarish-e-Bisbasa was carried out using HPTLC wherein the content of eugenol in the formulation and its ingredients was determined. The method was also found applicable for evaluation of stability of the formulation. Safety of the formulation was affirmed in mice and its anti-ulcer potential was evaluated using indomethacin induced acute experimental gastric ulcer in albino Wistar rats. The findings were also compared with modern anti-ulcer drug omeprazole. Pharmacokinetic evaluation of the formulation was carried out using piperine as a marker in rabbit plasma using validated HPLC method. The quality control parameters resulted from the scientific evaluation of Jawarish-e-Bisbasa can be used as reference standards by quality control/assurance unit of a pharmaceutical firm in order to have proper quality check over its preparation and processing. Findings of the present study will be used as a tool for scientific validation of this Unani formulation and add as a scientific support for its global acceptance.
Biography

Sunita Shailajan, a recognized guide for Ph.D. in Botany and Bioanalytical Sciences, has her specialization in areas like development of QC methods and preclinical studies for the raw materials and final herbal/ASU formulations and phytochemical extraction techniques. She is working on projects related to herbal medicines for menopausal problems (with North Eastern Hill University, Shillong) and Mycobacterium tuberculosis (with BARC unit). She is an Associate Professor in Botany, Convener of Research and heads the Herbal Research Lab and Animal Testing Centre at Ramnarain Ruia College. Her name is included in the 2007 th edition of Marquis Whos Who for my contribution in industry projects. She has received top reviewer award in 2011 from Journal of Ethnopharmacology (Elsevier). She has been awarded Best Teacher title and a special scholarship for her contribution in Industry Academia Linkage in Ruia College. She has published 70 research papers in the journals of high repute and has 2 patents to her credit with Marico Industries.

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