alexa Phytochemical Investigation Of Selaginella Bryopteris And Evaluation Of NO Inhibition On RAW 264.7 Macrophage
ISSN: 2167-0501

Biochemistry & Pharmacology: Open Access
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Share This Page

Additional Info

Loading
Loading Please wait..
 

International Conference on Pharmacognosy, Phytochemistry & Natural Products
October 21-23, 2013 Radisson Blu Plaza Hotel, Hyderabad, India

Agrahari U. C, Patel N. K and Bhutani K. K
Posters: Biochem & Pharmacol
DOI: 10.4172/2167-0501.S1.003
Abstract
Inflammation is one of the important causes, which are responsible for many diseases like cancer, rheumatoid arthritis, multiple sclerosis, diabetes etc. Pro-inflammatory cytokines (TNF-α, IFN-γ and IL-1β etc.) and NO are considered as pivotal mediators in inflammatory conditions like rheumatoid arthritis, Crohn?s disease etc. Thus inhibition of pro-inflammatory cytokines and NO production are important targets for treatment of inflammatory disorders. On the basis of their reported anti-inflammatory activity, several plants were selected and their respective extracts (n-hexane, DCM, EtOAc and MeOH extracts) were subjected for primary screening against pro-inflammatory mediators like TNF-α, IL-1β and NO, done for the above mentioned activity in RAW 264.7 cell line. Among these tested extracts the EtOAc extract of whole plants of Selaginella bryopteris were found to have maximum inhibitory activity against NO release. To identify the constituents responsible for the shown activity further phytochemical investigation is carried out which showed the presence of five biflavonoid (namely amentoflavone, hinokiflavone, heveaflavone. bilobetin, sequoiaflavone) and apigenin, luteolin and caffeic acid. Phytochemical investigation of the EtOAc extracts of whole plants of Selaginella bryopteris and their in vitro screening will be discussed in the poster.
Biography
Agrahari U. C completed his B.Pharm from UPTU Lucknow in 2006 and earned M.S. (Pharm) in Natural Products from NIPER SAS Nagar, Punjab, India in 2008. Currently, he is persuing Ph.D. in Natural Products from NIPER SAS Nagar Punjab, India. He also served as Assistant Professor in LPU Phagwara during 2008-2009 for one year. He has published one international paper in Natural Product research.
image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords