alexa Pilot Study Showed C-reactive Protein Was Significantly Reduced In Subjects With Progressive Osteoarthritis Consuming A Proprietary Dietary Supplement For 4 Weeks | 69521
ISSN: 2161-0533

Orthopedic & Muscular System: Current Research
Open Access

Like us on:

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

9th Orthopedics & Rheumatology Annual Meeting & Expo

Edward Andujar
LifePharm Global Network, USA
Keynote: Orthop Muscular Syst
DOI: 10.4172/2161-0533-C1-034
Abstract
Statement of the Problem: Osteoarthritis (OA) is a major cause of disability. It causes pain due to inflamed knee joints, involves cartilage degeneration and loss of collagen fibers. Current therapies have little influence on disease progression and are associated with adverse side effects. There is merit for use of safe compounds derived from natural sources for the treatment of OA. Increased serum levels of C-reactive protein (CRP) are observed in patients with OA. A low-level increase in CRP occurs in early disease and is predictive of progressive loss of joint space. CRP levels at presentation may help physicians identify individuals at risk of progression who may be suitable for intervention. Methodology & Theoretical Orientation: Five subjects experiencing joint stiffness and pain were recruited by the physician. They signed voluntary informed consent for routine blood sampling and supplement ingredients. Subjects consumed one supplement (Laminine®, LifePharm Inc. Lake Forest, CA) in the morning and one in the evening for 4 weeks. Subjects were not asked to modify behaviors or medical regimens. Findings: A t test for related samples was performed comparing baseline and 4 week final CRP values (p=0.02562). A sign test (p=0.03125) and Wilcoxon matched-pairs signed-ranks test (p=0.03125) were performed to confirm results as sample size was small. Conclusion & Significance: This pilot study indicated the supplement supported a reduction in CRP in subjects with mild to moderate OA symptoms. The supplement contains proprietary fertilized chicken egg extract, fish and pea proteins. Recent human skin fibroblast experiments showed the unprocessed egg used in Laminine®, contained active Platelet Derived Growth Factor, Transforming Growth Factor β-1, Lysyl oxidase, Fibroblast Growth Factor 2 and chondroitin. When the proprietary egg was added to the cells there was highly significant up-regulation of collagen, elastin and fibronectin production compared to controls. These receptors and mechanisms are also found in connective tissues. Results warrant further studies.
Biography

Edward Andujar has received his Medical degree from Harvard Medical School and did his Residency at Temple University Hospital in Philadelphia, PA. He had a general practice for 20 years. With the growth of the dietary supplement industry and his interest in the field, he has joined LifePharm Global Network in 2011 as a Research Scientist. He designs protocols with clinical physicians to investigate safety and efficacy of various dietary supplements. His preliminary work of investigating Laminine® and other dietary supplements appears in the Physician’s Desk Reference. He is devoted to educating consumers and other health care professionals in the clinical efficacy of nutritional supplements and their potential benefits.

Email: [email protected]

image PDF   |   image HTML
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
Leave Your Message 24x7