alexa Predictive Value Of Primary-tumor Volume-based Parameters On F-18 FDG PET/CT For Axillary Lymph Node Metastasis In Invasive Breast Cancer
ISSN: 2471-8556

Oncology & Cancer Case Reports
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Share This Page

Additional Info

Loading
Loading Please wait..
 

15th World Congress on CANCER THERAPY, BIOMARKERS & CLINICAL RESEARCH
December 05-07, 2016 Philadelphia, USA

Bong-Il Song
Dongsan Medical Center, Keimyung University School of Medicine, Korea
Posters & Accepted Abstracts: Oncol Cancer Case Rep
DOI: 10.4172/2471-8556.C1.003
Abstract
Objectives: This study assessed whether volume-based parameters of primary-tumor measured by preoperative F-18 FDG PET/CT could have the predictive value for Axillary Lymph Node (ALN) metastasis prediction in invasive ductal breast cancer (IDC). Methods: A total of 57 female patients (mean age, 49.4 ± 9.5) with IDC who underwent surgical resection of primary tumor with sentinel lymph node biopsy and/or axillary LN dissection without any neoadjuvant treatment were analyzed. Metabolically active tumor regions were delineated on pretreatment PET scans semi-automatically using custom software. Maximum standardized uptake value (SUVmax) and metabolic tumor volume (MTV) were used. To obtain the MTV, we used a threshold of SUV 2.0, 25%, 50% and 75% for the SUVmax. Results: LN metastasis was found in 20 patients (35.1%). MTV-75% and MTV-50% were significantly higher in patient with LN metastasis (P = 0.005 and 0.015). However, SUVmax, MTV-2.0, and MTV-25% showed no significant difference. On receiver operating characteristic (ROC) curve analysis, MTV-75% (area under the curve (AUC) = 0.726, 95% confidence interval [95% confidence interval (CI)] 0.591–0.839) and MTV-50% (AUC = 0.696, 95% CI 0.560–0.811) showed good predictive performance for LN metastasis. Conclusion: MTV-75% and MTV-50% as determined by F-18 PET/CT demonstrated a statistically significant correlation with LN metastasis in patients with IDC. Therefore, patients with high values of MTV on pretreatment F-18 FDG PET/CT should be cautiously evaluated for LN metastasis.
Biography

Email: [email protected]

image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords