alexa Predictors Of Reducing Low-density Lipoprotein Cholesterol (LDL-C) Among Thai HIV-infected Adults Receiving Antiretroviral Regimen For At Least 3 Months
ISSN 2155-6113

Journal of AIDS & Clinical Research
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Share This Page

Additional Info

Loading Please wait..

2nd International Conference on HIV/AIDS, STDs, & STIs
October 27-29, 2014 Embassy Suites Las Vegas, USA

Saipin Chotivichien, Wisit Prasithsirikul, Weerawat Manosuthi, Sangsom Sinawat and Roger Detels
Accepted Abstracts: J AIDS Clin Res
DOI: 10.4172/2155-6113.S1.009
Background: HIV-infected patients receiving antiretroviral therapy experience metabolic syndrome, including hyperlipidemia, particularly in low-density lipoprotein cholesterol (LDL-C), which is one of those significant predictors of cardiovascular disease (CVD). Reducing LDL-C has been reported to be associated with a reduced rate of cardiovascular outcomes. The objective of this study was to identify predictors of reducing LDL-C in HIV-infected patients with abnormal LDL-C who were on stable antiretroviral therapy for at least 3 months. Methods: We conducted a randomized, 24-week study in HIV-infected patients with dyslipidemia who were on antiretroviral therapy. Participants were randomly assigned into two groups. The intervention group received individual counseling with a nutritionist for 7 sessions, whereas the control group received general diet information at baseline and subsequent annual visits as standard care. All HIV positive patients with an abnormal LDL-C were followed up for 24 weeks. Predictors (measured at baseline) associated with a reduction of LDL-C of at least 10 mg/dL in HIV-infected patients were identified. Results: Seventy-two patients were randomly assigned and 64 (89%) participants completed the lipid profile tested at 24 weeks of follow up. A reduction of LDL-C at least 10 mg/dL was significantly associated with higher percentage of polyunsaturated fat (adjusted OR=1.50, 95% CI=1.05, 2.14). A significant reduction of at least 10 mg/dL was also observed with good knowledge of dyslipidemia (adjusted OR=6.03, 95% CI=1.40, 25.96). Conclusions: The study demonstrated that knowledge of dyslipidemia and dietary consumption are important predictors for a reduction in LDL-C of at least 10 mg/dL. We recommend diet modification (substitution of saturated fatty acid with polyunsaturated fatty acid) and education about dyslipidemia should be provided to every HIV-treated dyslipidemia patient.
image PDF   |   image HTML
Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version