alexa Prescription Audit With Special Emphasis On Drug-drug Interactions Study In A Tertiary Care Teaching Hospital
ISSN: 2376-0419

Journal of Pharmaceutical Care & Health Systems
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10TH Asia-Pacific Pharma Congress
May 08-10, 2017 Singapore

Ajay Chandra
Norvic International Hospital, Nepal
Posters & Accepted Abstracts: J Pharma Care Health Sys
DOI: 10.4172/2376-0419-C1-021
Abstract
Drug-Drug Interactions (DDIs) may be defined as, interaction of two or more drugs in such a manner that the effectiveness or toxicity of one or more drugs is altered. DDI in patients receiving multidrug therapy is a major concern. Although drug-drug interaction constitute only small portion of adverse drug reactions, they are often predictable and therefore avoidable or manageable. The aim of our present study was to assess the incidence and severity of DDIs in patients admitted in a tertiary care teaching hospital. A prospective, observational study was carried out for a period of 6 months (Jan–June 2013). During the study period, a total of 300 prescriptions were analyzed and was found that 242 prescriptions had DDI. The average number of drugs in each prescription was 8. Regarding the severity of clinical results, the interaction was classified as minor, moderate, major from the 242 prescriptions. The 40 major DDIs are reported from 32 prescriptions, leading to increased hospitalisation and health care cost of the patients. DDI was identified by using micromedex, Stockley’s drug interaction book and other reputed journals. Many physicians were unaware of various DDIs. Hence, education, computerised prescribing system and drug information along with collaborative drug selection and pharmaceutical care are strongly encouraged for physicians and pharmacists to avoid such incidences.
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