alexa Prevalence Of Dengue Virus And Their Serotypes Causing Infection In Eastern UP, India
ISSN: 2161-0517

Virology & Mycology
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Share This Page

Additional Info

Loading Please wait..

10th World Congress on Virology and Mycology
May 11-12, 2017 Singapore

Amresh Kumar Singh, Ruchi Mishra, Jayesh Pandey and Kusum Jasuja
BRD Medical College Gorakhpur, India
ScientificTracks Abstracts: Virol-mycol
DOI: 10.4172/2161-0517-C1-020
Statement of the Problem: Dengue is one of the most serious mosquito borne viral infections and in India it has dramatically expanded over the last few decades, with rapidly changing epidemiology. The spectrum of manifestations is ranging from asymptomatic/mild to dengue hemorrhagic fever (DHF), to a shock syndrome (DSS). Recent research shows that there is a clear shift in dengue virus (DENV) having mortality 0.5–3.5% in DENV-2. So, this study was conducted to know the prevalence of dengue by different methods, serotypes and its impact in epidemiology, mortality in UP, India. Methodology & Theoretical Orientation: Prospectively designed study was performed and all laboratory records were analyzed. Blood samples were tested for dengue NS1 antigen, IgM antibodies, and nucleic acid detection by; dengue early NS1 enzyme linked immune sorbent assay (ELISA), IgM capture ELISA, and real time reverse transcriptase PCR (RT-PCR), respectively. Descriptive statistics were used and data were expressed in proportions. Nested RT-PCR was performed for serotyping. Findings: Out of total 863 samples tested, 203 (23.52%) were found positive for dengue virus infection by combination of different methods with male preponderance (65%). Seasonal trend showed a gradual increase; starting from July with a peak in September (34.5%). The most common presentation was fever (97%), only 1% cases presented with hemorrhagic manifestations. Out of total of 203 cases, 176 (86.7%) patients had fever, 16 (7.9%) DHF and 11 (5.4%) had DSS. Dengue IgG prevalence increased with age, with the lowest (16.3%) in <20 years and the highest (78.3%) in 20-40 years. The range of platelet count was; 1,69,000-11000/cumm. A total of 189/863 (21.9%) specimens were positive for NS1, 64/863 (7.4%) for IgM and 177/863 (20.5%) positive by nested RT-PCR. Of 203 positive cases, maximum serotypes were 123 (60.6%) for DENV-2 and mixed serotypes in 06 (2.96%) patients. Mortality was seen in 15 cases (7.4%), with maximum occurring in 2016. Conclusion & Significance: Dengue has established its transmission and high prevalence (23.52%) in UP with predominantly affecting adult males and preponderance by DENV-2 virus (60.6%). This study thus emphasizes the need for continuous sero-epidemiological diagnosis/surveillance for effective dengue control in India.

Amresh Kumar Singh has expertise in different disciplines of Clinical Microbiology and Infectious Diseases Evaluation and passion in improving the health and wellbeing of people living in Eastern UP, India. He has published many national as well as international journals and has teaching experience in teaching MBBS students, BSc (Nursing), MSc (Microbiology) and MD. He participated in project for detection of antimicrobial resistance in Gram negative bacilli, and Gram positive cocci like, ESBLs, AmpC, MBLs, MRSA, VRE etc. He worked on diagnostic mycobacteriology (culture and antimicrobial sensitivity techniques including culture on standard media, BacT/ALERT® 3D system, Mycobacteria growth indicator tube (MGIT) and Mycobacterium tuberculosis direct detection methods), antimicrobial susceptibility testing in M. tuberculosis complex (MTBC) and NTM (conventional and DNA-based methods) like line probe assay and mutational study; Virologyespecially in dengue virus, HIV, enteroviruses (AES), viral encephalitis, acute hemorrhagic viral infection for their diagnosis and; tissue culture techniques for isolation and identification of different medically important viruses for PCR (conventional, nested, Real-time RT-PCR), DNA sequencing, spoligotyping, pulse-field gel electrophoresis, etc.


image PDF   |   image HTML

Relevant Topics

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

1-702-714-7001Extn: 9037

Business & Management Journals


1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

1-702-714-7001Extn: 9042

General Science

Andrea Jason

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

1-702-714-7001Extn: 9042

© 2008- 2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version